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Paper Title
Li- Fraumeni Syndrome- A Review
Authors
Ajrish George
Keywords
Li- Fraumeni syndrome, physiology, management
Abstract
Abstract Aim The aim is to do a literature review on Li-Fraumeni syndrome Background Li-Fraumeni syndrome is a rare cancer predisposition hereditary disorder characterised as autosomal dominant. It was named after two American physicians, Frederick per Li and Joseph F. Fraumeni, who recognized the syndrome after reviewing the medical records and death certificate of 648 childhood rhabdomyosarcoma patients. The syndrome is linked to germ line mutations of p53 tumour suppressor gene, which encodes a transcription factor (p53) that normally regulates the cell cycle and prevents genomic mutation by phagocytises or enabling the programmed cell death of the defective cell. In this article, a brief account on the Li-Fraumeni syndrome is attempted.
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IJRTI — journal style
"Li- Fraumeni Syndrome- A Review", IJRTI - International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.2, Issue 8, page no.154 - 159, August-2017, Available :https://ijrti.org/papers/IJRTI1708028.pdf
APA — 7th edition
George, A. (2017). Li- Fraumeni Syndrome- A Review. International Journal for Research Trends and Innovation, 2(8), 154 - 159. https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028
MLA — 9th edition
George, Ajrish. "Li- Fraumeni Syndrome- A Review." International Journal for Research Trends and Innovation, vol. 2, no. 8, 2017, pp. 154 - 159, https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028.
Chicago — 17th, bibliography
George, Ajrish. "Li- Fraumeni Syndrome- A Review." International Journal for Research Trends and Innovation 2, no. 8 (2017): 154 - 159. https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028.
Harvard — author–date
George, A. (2017) 'Li- Fraumeni Syndrome- A Review', International Journal for Research Trends and Innovation, 2(8), pp. 154 - 159. Available at: https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028
IEEE — numbered reference
A. George, "Li- Fraumeni Syndrome- A Review," IJRTI, vol. 2, no. 8, pp. 154 - 159, Aug. 2017.
Vancouver — biomedical
George A. Li- Fraumeni Syndrome- A Review. IJRTI. 2017 Aug;2(8):154 - 159.
AMA — 11th edition
George A. Li- Fraumeni Syndrome- A Review. IJRTI. 2017;2(8):154 - 159. Accessed at https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028
BibTeX — Zotero, Mendeley, LaTeX
@article{IJRTI1708028,
author = {Ajrish George},
title = {Li- Fraumeni Syndrome- A Review},
journal = {International Journal for Research Trends and Innovation},
volume = {2},
number = {8},
pages = {154 - 159},
year = {2017},
month = {August},
issn = {2456-3315},
url = {https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - George, Ajrish
TI - Li- Fraumeni Syndrome- A Review
T2 - International Journal for Research Trends and Innovation
JA - IJRTI
VL - 2
IS - 8
PY - 2017
SN - 2456-3315
UR - https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028
SP - 154
EP - 159
ER -
Issue
Volume 2 Issue 8,
August-2017
Pages : 154 - 159
Other Publication Details
Paper Reg. ID
IJRTI_170488
Published Paper ID
IJRTI1708028
Downloads
205,639
Research Area
Biological Science
Country
Chennai, Tamil nadu, India
Published
August 2017
Published Paper PDF
https://ijrti.org/papers/IJRTI1708028.pdf
Published Paper URL
https://ijrti.org/viewpaperforall.php?paper=IJRTI1708028
About Publisher
International Journal for Research Trends and Innovation
Published by IJRTI (JW Publication)
2456-3315
ISSN
10.57
Impact Factor
2016
ESTD Year
Open
Access
Impact Factor 10.57 calculated by Google Scholar and Semantic Scholar.
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Declarations
Funding
No external funding was received for this study.
Conflict of Interest
The authors declare that they have no conflict of interest.
Acknowledgements
The authors would like to thank the reviewers and the editorial board of International Journal for Research Trends and Innovation for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.
