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The present study reports physicochemical characterization, antimicrobial and Wound Healing activity of extracts from Vigna Radiata stem bark collected from local region of Nanded, Maharashtra, India. Different physical parameters like ash values, extractive value, Loss on drying, solubility etc were evaluated for powdered drug. The extracts were obtained from Soxhlet method by using ethyl acetate and ethanol as solvents for extraction and subjected for preliminary physicochemical evaluation. Total phenolic and flavonoids content were also analyzed. The presence of primary and secondary metabolites such as carbohydrate, proteins, alkaloids, phenolic compounds, saponins was confirmed through preliminary phyto-chemical analysis. Antimicrobial activity showed strong antibacterial and antifungal activities with increase in concentration of ethyl acetate and ethanol leaf extracts. The In-Vivo wound Healing activity of Vigna Radiata stem bark was evaluated by excision wound model in rats using Soframycin as a standard. Both the extracts showed significant reduction in wound size. The result suggest that Vigna Radiata stem bark extracts possess wound healing activity and this might be due to flavonids. Phenolic compound, steroid and proteins present in extract.
"PHYTOCHEMICAL AND PHARMACOLOGICAL EVALUATION OF VIGNA RADIATA STEM BARK EXTRACTS FOR ITS WOUND HEALING ACTIVITY", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 9, page no.29 - 40, September-2020, Available :http://www.ijrti.org/papers/IJRTI2009004.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator