AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION
IJRTI2106015
Volume 6, Issue 6
Page 84 - 90
June 2021
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ISSN2456-3315
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Paper Title
AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION
Authors
Arti , Anupama Diwan , Rani Mansuri
Keywords
Diffusion, In Vitro Release Testing (IVRT), In-Line Cell (ILC), Validation and application.
Abstract
In vitro release testing (IVRT) is used to check the release characteristics of any semi-solid topical drug formulations. A various diffusion system such as Franz diffusion cell, vertical diffusion cell system, horizontal diffusion cell system, static diffusion cell, side by side diffusion cell, immersion cell, flow through diffusion cell, are being used as a manual release system, but suffer from numerous manual errors. Therefore, valid and standard diffusion system is desirable for determination of release characteristics of topical formulations. To overcome these errors, recently, the manual system has been replaced by automated in-line diffusion cell system. This automated IVRT offers many advantages over manual system that include continuous flow of receptor solution, automated sampling, required less time, also safeguarding the hazards of the environment by limiting physical contacts, thereby overcome all the problems which are associated in manual diffusion system. An automated IVRT diffusion system is an advanced technique that is being used for development and evaluation of topical formulations. In this review, we are demonstrating the advanced IVRT diffusion system along with its various validation parameters and factors associated with sample analysis. Furthermore, the potential advantages and future prospective of it are also discussed.
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IJRTI — journal style
"AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION", IJRTI - International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.6, Issue 6, page no.84 - 90, June-2021, Available :https://ijrti.org/papers/IJRTI2106015.pdf
APA — 7th edition
Arti, Diwan, A., & Mansuri, R. (2021). AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION. International Journal for Research Trends and Innovation, 6(6), 84 - 90. https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015
MLA — 9th edition
Arti, et al. "AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION." International Journal for Research Trends and Innovation, vol. 6, no. 6, 2021, pp. 84 - 90, https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015.
Chicago — 17th, bibliography
Arti, Anupama Diwan, and Rani Mansuri. "AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION." International Journal for Research Trends and Innovation 6, no. 6 (2021): 84 - 90. https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015.
Harvard — author–date
Arti, Diwan, A. and Mansuri, R. (2021) 'AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION', International Journal for Research Trends and Innovation, 6(6), pp. 84 - 90. Available at: https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015
IEEE — numbered reference
Arti, A. Diwan and R. Mansuri, "AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION," IJRTI, vol. 6, no. 6, pp. 84 - 90, Jun. 2021.
Vancouver — biomedical
Arti, Diwan A, Mansuri R. AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION. IJRTI. 2021 Jun;6(6):84 - 90.
AMA — 11th edition
Arti, Diwan A, Mansuri R. AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION. IJRTI. 2021;6(6):84 - 90. Accessed at https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015
BibTeX — Zotero, Mendeley, LaTeX
@article{IJRTI2106015,
author = {Arti and Anupama Diwan and Rani Mansuri},
title = {AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION},
journal = {International Journal for Research Trends and Innovation},
volume = {6},
number = {6},
pages = {84 - 90},
year = {2021},
month = {June},
issn = {2456-3315},
url = {https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Arti
AU - Diwan, Anupama
AU - Mansuri, Rani
TI - AN OVERVIEW ON AUTOMATED IN VITRO RELEASE TESTING (IVRT) FOR TOPICAL FORMULATION
T2 - International Journal for Research Trends and Innovation
JA - IJRTI
VL - 6
IS - 6
PY - 2021
SN - 2456-3315
UR - https://ijrti.org/viewpaperforall.php?paper=IJRTI2106015
SP - 84
EP - 90
ER -
International Journal for Research Trends and InnovationPublished by IJRTI (JW Publication)
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Declarations
Funding
No external funding was received for this study.
Conflict of Interest
The authors declare that they have no conflict of interest.
Acknowledgements
The authors would like to thank the reviewers and the editorial board of International Journal for Research Trends and Innovation for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.