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Oral films are an original methodology for the improvement of orally crumbling dose structures. They are thin, exquisite for all intents and purposes and can be made into different sizes and shapes like rectangular or round. The strips might be adaptable or weak, obscure or straightforward. Oral films are comprised of different hydrophilic and hydrophobic polymers to give rapid disintegration on the tongue without the requirement for water. The point of the current investigation is to foster quick dissolving films of tramadol Hydrochloride by improving drug dissolution in the oral pit. The advancement of the films diminishes the analgesic impact in less time and expands the patient's consistence. Thusly the pre-arranged films were assessed for different boundaries like physical appearance and surface of the film, thickness of the film, collapsing perseverance, moisture take-up, uniformity of weight and drug content, swelling index, in vitro disintegration considers, and in vitro dissolution contemplates. Stability studies were likewise performed. However every one of the plans similarly passed the assessment boundaries, it is presumed that oral thin films containing 400 mg of sodium alginate as the polymer in view of better dissolution profile.
Keywords:
Oral film, Tramadol HCL, Fast dissolving, Thin film.
Cite Article:
"FORMULATION DEVELOPMENT AND EVALUATION OF FAST DISSOLVING FILM OF TRAMADOL HCL ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.6, Issue 10, page no.117 - 121, October-2021, Available :http://www.ijrti.org/papers/IJRTI2110013.pdf
Downloads:
000204816
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator