UGC CARE norms ugc approved journal norms IJRTI Research Journal

Click Here

International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

Call For Paper

For Authors

Forms / Download

Published Issue Details

Editorial Board

Other IMP Links

Facts & Figure

Impact Factor : 8.14

Issue per Year : 12

Volume Published : 7

Issue Published : 79

Article Submitted : 5505

Article Published : 3032

Total Authors : 7767

Total Reviewer : 540

Total Countries : 67

Indexing Partner


This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Published Paper Details
Paper Title: Synoptic Review On Ophthalmic In-SITU Gel System
Authors Name: Prerana S Husukale , Dr. I.D.Gonjari
Download E-Certificate: Download
Author Reg. ID:
Published Paper Id: IJRTI2208221
Published In: Volume 7 Issue 8, August-2022
Abstract: Ophthalmic drug delivery is one of the most fascinating and difficult endeavours facing pharmaceutical scientists. The main issue encountered by pharmaceutical scientists is rapid precorneal elimination of the drug, resulting in poor bioavailability and therapeutic response due to high tear fluid turnover and dynamics. These benefits, including ease of administration, decreased frequency of administration, improved patient compliance, and comfort, have sparked interest in in situ forming polymeric delivery systems. The development of gels, which allow for the sustained and controlled release of drugs, is dependent on variables including temperature variation, pH changes, the presence of ions, and ultraviolet radiation. In situ-forming gels are liquid when applied, go through a phase change in the ocular cul de sac to become visco-elastic gel, and respond to environmental changes as a result. A significant number of novel temperature, pH, and ion induced in situ-forming systems have been reported in the recent years for sustained ophthalmic drug delivery. Each system has unique benefits and drawbacks. The selection of a specific gel is based on its inherent qualities and intended therapeutic use. In situ gels are now employed as delivery systems for drugs that have both local and systemic effects. The fundamentals of the in situ gel system are discussed in this review. Such devices are easier to produce from a manufacturing standpoint, which reduces investment and manufacturing costs.
Keywords: In-Situ Gel, Poor bioavailability, Controlled release, Sustained release, Ophthalmic
Cite Article: "Synoptic Review On Ophthalmic In-SITU Gel System", International Journal of Science & Engineering Development Research (, ISSN:2455-2631, Vol.7, Issue 8, page no.1361 - 1365, August-2022, Available :
Downloads: 000177625
ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2208221
Registration ID:183803
Published In: Volume 7 Issue 8, August-2022
DOI (Digital Object Identifier):
Page No: 1361 - 1365
Country: Satara, Maharashtra, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL :
Published Paper PDF:
Share Article:

Click Here to Download This Article

Article Preview
Click Here to Download This Article

Major Indexing from
Google Scholar ResearcherID Thomson Reuters Mendeley : reference manager : cornell university library Research Gate CiteSeerX DOAJ : Directory of Open Access Journals
DRJI Index Copernicus International Scribd DocStoc

ISSN Details

ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

DOI (A digital object identifier)

Providing A digital object identifier by DOI.ONE
How to Get DOI?


Open Access License Policy

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Creative Commons License This material is Open Knowledge This material is Open Data This material is Open Content

Important Details

Social Media

Join RMS/Earn 300


Indexing Partner