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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 113
Article Submitted : 18018
Article Published : 7746
Total Authors : 20484
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| Paper Title: | CASE REVIEW ON EFFECTS OF SODIUM FLOURIDE ON LIVER |
| Authors Name: | Mantri Sneha , G. Supriya Reddy , V. V. Rajesham , T. Rama Rao |
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IJRTI_187351
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| Published Paper Id: | IJRTI2306119 |
| Published In: | Volume 8 Issue 6, June-2023 |
| DOI: | |
| Abstract: | The process of excessive ingestion of fluoride over a prolonged period is called chronic fluorosis. It endangers the health of humans as well as animals. Sodium Fluoride causes toxic effects when given in high doses. Various cases of effects of sodium fluoride on the liver of various animals are studied. Sodium fluoride caused marked increase in serum transaminases like Alanine aminotransferase, Aspartate aminotransferase and Alkaline phosphatase along with inhibition of activation of antioxidants enzymes, Glutathione peroxidase and superoxide dismutase. NaF stimulates increase in hepatic content of Hydrogen Peroxide (H2O2), Nitric Oxide (NO), Protein Carbonyls and Oxidation protein products. It also increases the levels of inflammatory markers (NF-Kβ, IL-1β, TNF-α). It also causes oxidative stress and necrosis. |
| Keywords: | Sodium fluoride, Alanine aminotransferase, Aspartate aminotransferase, alkaline phosphatase, inflammatory markers |
| Cite Article: | "CASE REVIEW ON EFFECTS OF SODIUM FLOURIDE ON LIVER", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 6, page no.786 - 789, June-2023, Available :http://www.ijrti.org/papers/IJRTI2306119.pdf |
| Downloads: | 000205009 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2306119
Registration ID:187351
Published In: Volume 8 Issue 6, June-2023
DOI (Digital Object Identifier):
Page No: 786 - 789 Country: Medchal , Telangana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2306119 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2306119 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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