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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Evaluation Of Safety Of Azilsartan And Olmesartan In Patients Of Hypertension: Randomized Controlled Trial. |
| Authors Name: | Dr.Deeksha Sharma , Dr Dinesh Kansal , Dr Dhiraj Kapoor , Dr Atal Sood |
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| Author Reg. ID: |
IJRTI_187389
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| Published Paper Id: | IJRTI2306144 |
| Published In: | Volume 8 Issue 6, June-2023 |
| DOI: | https://doi.org/10.56975/ijrti.v8i6.187389 |
| Abstract: | Background: Renin‐angiotensin aldosterone system (RAAS) inhibitor either angiotensin‐converting enzyme inhibitor or an angiotensin II receptor blocker (ARB) plus diuretic is a widely used for treatment of hypertension. Objective: To evaluate safety of azilsartan and olmesartan in patients of hypertension. Material and methods: A randomized, prospective, open label, comparative study was carried out in Pharmacology and Medicine department at Dr. R.P.G.M.C. Kangra at Tanda, HP. The study stretched over one year and haemoglobin (Hb), renal function test (RFT), liver function test (LFT), serum electrolytes were monitored at first, third and sixth month. Out of 69 patients, 35 patients in group A were prescribed tablet azilsartan 40 mg/day and 34 patients in group B were prescribed tablet olmesartan 20 mg/day along with chlorthalidone 12.5 mg/day in both the groups. Statistical analysis: Data was presented as mean + SD. Student’s t-test was used for comparing continuous variables between the two groups. P value < 0.05 was considered significant Results: Both the groups had normal range of haemoglobin, renal function test , liver function test and serum electrolyte over 6 months of period. There was no hepatotoxicity, nephrotoxicity, electrolyte imbalance and haematological toxicity observed in patients. Conclusion: Azilsartan and olmesartan were safe in patients of hypertension |
| Keywords: | Azilsartan, Olmesartan, Hypertension, Safety |
| Cite Article: | "Evaluation Of Safety Of Azilsartan And Olmesartan In Patients Of Hypertension: Randomized Controlled Trial.", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 6, page no.960 - 967, June-2023, Available :http://www.ijrti.org/papers/IJRTI2306144.pdf |
| Downloads: | 000205244 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2306144
Registration ID:187389
Published In: Volume 8 Issue 6, June-2023
DOI (Digital Object Identifier): https://doi.org/10.56975/ijrti.v8i6.187389
Page No: 960 - 967 Country: kangra, himachal pradesh, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2306144 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2306144 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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