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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | A Comparative Analysis of Novel Intracanal Medicaments and Chlorhexidine Against E Faecalis - An Invitro Study |
| Authors Name: | Dr. Ramesh Chandra , Dr. Supratim Tripathi , Dr Ankita Mehrotra , Dr Mariyam Khan, Dr. Nurez Anwar , Dr. Aditya Bhagat |
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IJRTI_187756
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| Published Paper Id: | IJRTI2307138 |
| Published In: | Volume 8 Issue 7, July-2023 |
| DOI: | |
| Abstract: | Introduction: The success of root canal therapy heavily relies on the thorough disinfection of the root canal system, which necessitates the use of an intra-canal medicament. Persistent/secondary intracanal infection associated with endodontic treatment failure is often attributed to Enterococcus faecalis, the most found species. With the developing resistance among the microorganisms, new strategies for eradication are needed. Aim: The present study was designed with an aim to evaluate whether a naturally occurring antibiotic “nisin” can be used as a potent intra canal medicament in combination with frequently used intra canal medicaments for eradication of E. faecalis from intra canal space Objective: The present study compares the antibacterial effect of various combinations of Nisin with Metronidazole, with Calcium Hydroxide with Chlorhexidine and antibacterial effect of 2 % Chlorhexidine alone against E Faecalis. Materials and Methods: In the present study, the effectiveness of four antibacterial materials, 10% Nisin with 5% Metronidazole (i.e Group I), 10% Nisin with Calcium Hydroxide (i.e Group II), 10% Nisin with 2% Chlorhexidine (i.e Group III), and 2% Chlorhexidine (i.e Group IV), were taken. The antibacterial efficacy of these medicaments against Enterococcus faecalis was assessed in vitro using disc diffusion method. Results: Group IV 2% Chlorhexidine exhibited maximum inhibition of bacterial growth followed by Group III 10% Nisin with 2% Chlorhexidine, Group II 10% Nisin with Calcium Hydroxide and least by Group I 10% Nisin with 5% Metronidazole. Conclusion: Group IV 2% Chlorhexidine was the most effective medicament against E. Faecalis compared to other combinations but nisin also holds a promising potential against Enterococcus faecalis." |
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| Cite Article: | "A Comparative Analysis of Novel Intracanal Medicaments and Chlorhexidine Against E Faecalis - An Invitro Study", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 7, page no.968 - 975, July-2023, Available :http://www.ijrti.org/papers/IJRTI2307138.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2307138
Registration ID:187756
Published In: Volume 8 Issue 7, July-2023
DOI (Digital Object Identifier):
Page No: 968 - 975 Country: -, -, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2307138 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2307138 |
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ISSN: 2456-3315
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