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Carotid atherosclerotic disease, characterized by the accumulation of plaque in the carotid arteries, poses a significant risk of stroke due to reduced blood flow to the brain. This research article presents a groundbreaking study focusing on the development of a novel self-expandable stent designed specifically for the carotid artery. The stent, composed of a nitinol alloy, incorporates a biodegradable mesh made of Poly (lactic-co-glycolic acid) (PLGA). Its tapered design ensures optimal alignment with the carotid artery’s natural anatomical attributes. The primary objective of this stent system is to enhance performance by minimizing restenosis and stent thrombosis occurrences. The biodegradable mesh covering creates a favorable environment within the blood vessel, effectively reducing the risk of clot formation. This is of utmost importance as clots can lead to severe complications such as vessel blockages, heart attacks, or strokes. The research significantly contributes to ongoing efforts in improving treatment options for carotid atherosclerotic disease and mitigating associated risks. Through meticulous in-vitro studies, the real-time degradability of the biodegradable polymeric mesh has been successfully assessed, laying the foundation for potential clinical applications. The development of this self-expandable stent offers a promising solution for patients suffering from carotid atherosclerotic disease. Its unique design, coupled with the biodegradable mesh, aims to enhance long-term efficacy, minimize complications, and improve overall patient outcomes. Our future studies would focus on rigorous in-vivo evaluations and clinical trials to further validate the potential of this stent in revolutionizing the treatment landscape for carotid atherosclerotic disease.
"Revolutionizing Carotid Artery Disease Treatment: Advancement in Self-Expandable Stent with Biodegradable Mesh Covering", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 9, page no.265 - 275, September-2023, Available :http://www.ijrti.org/papers/IJRTI2309032.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator