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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Volume 10 | Issue 12
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Impact Factor : 8.14
Issue per Year : 12
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| Paper Title: | A Prospective Observational Study on Drug Dosage Adjustment in Chronic Kidney Disease Patients at Tertiary Care Hospital |
| Authors Name: | Krishna Kumar Mahato , Balakeshwa Ramaiah , Priscillamol R Mathew , Dhirendra Yadav |
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IJRTI_188722
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| Published Paper Id: | IJRTI2312072 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | The aim of this study was to determine the number of medicines specified being meetly acclimated grounded on the cases renal function according to the guidelines. Most important drug related problem in case with CKD is drug crimes. Numerous drugs and their metabolites are excreted through renal route. Therefore, acceptable renal function is important to avoid toxin. The materials and methods of this is a prospective observational study on medicine cure adaption study which was grounded on the collection of data on the diurnal visit to department of medicine, HICU and nephrology department in tertiary care unit. The study involves the analysis of specifics and cure adaption needed for CKD cases and compared with standard guidelines (K/DOQI) The cases who meet the criteria were involved in this study. The result of this study is total of 1063 specified medicines for 74 cases, 76(7%) medicines need a dosing adaption in renal failure and 989 (93%) medicines do not need. From 76 medicines that need a dosing adaption, the cure of 31(40%) medicines were acclimated and 45 (60%) medicines were not. Medicines that need an adjustment are meropenem, amoxicillin clavulanate, piperacillin tazobactam, cefoperazone sulbactam, amikacin, ranitidine and rosuvastatin. The finding of this study showed that the errors in dose of medications in CKD patients were high. Many drugs needed to be adjusted depending on the patient’s kidney functions. A team work of physicians with a pharmacist or a clinical pharmacologist is necessary for the detection and prevention of dose related medication errors which will improve the therapeutic outcomes and reduced the toxicity and side effects in patients with CKD. |
| Keywords: | chronic kidney disease, glomerular filtration rate, end stage renal disease, nephrology, dosage adjustment |
| Cite Article: | "A Prospective Observational Study on Drug Dosage Adjustment in Chronic Kidney Disease Patients at Tertiary Care Hospital", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 12, page no.507 - 511, December-2023, Available :http://www.ijrti.org/papers/IJRTI2312072.pdf |
| Downloads: | 000205106 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2312072
Registration ID:188722
Published In: Volume 8 Issue 12, December-2023
DOI (Digital Object Identifier):
Page No: 507 - 511 Country: Bangalore, Karnataka , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2312072 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2312072 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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