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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | UTILIZATION OF DUAL ANTIPLATELET THERAPY IN CARDIOVASCULAR DISEASE PATIENTS – A PROSPECTIVE OBSERVATIONAL STUDY |
| Authors Name: | Poulami Debbarma , Dr. Shibi Mary Thomas , Dr. Balakeshwa Ramaiah |
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IJRTI_189182
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| Published Paper Id: | IJRTI2402036 |
| Published In: | Volume 9 Issue 2, February-2024 |
| DOI: | |
| Abstract: | Aim: To study the utilization of DAPT and optimal dosage and duration of DAPT in cardiovascular disease patients. Materials and methods: In this study 100 patients were recruited who were diagnosed with cardiovascular disease such as ACS, CAD, PAD, IHD, UA, stroke and revived their prescription to evaluate adherence to guidelines on prescription pattern of DAPT with the current AHA/ACC, ESC and AHA/ASA guidelines. Another aspect of the study was to look for any bleeding events experienced by the patient during the therapy by cross verifying their medical charts, history and also laboratory parameters like hemoglobin, hematocrit, platelet levels, PTT and INR levels. Results: Among the 100 patients who were part of the study, ticagrelor and aspirin made up the bulk of the DAPT prescriptions (55%) compared to clopidogrel and aspirin (45%). According to the study, 2% of patients had a DAPT prescription for less than a month, 47% for 1-3 months, 20% for 4-6 months, 15% for 7-12 months, and 10% for more than 12 months. In all, 55% of patients received prescriptions in accordance with ESC recommendations, 73% with AHA/ACC guidelines, and 75% with ASA/AHA guidelines for stroke. Ten patients in all reported bleeding incidents while receiving treatment. Assessment of alterations in laboratory parameters, including hemoglobin, platelet count, serum creatinine, aPTT, and PTT, in patients experiencing bleeding episodes. Conclusion: The study concludes that the prescription pattern is followed according to the standard guidelines for optimal dosing and duration in cardiovascular disease. DAPT is associated with the occurrence of bleeding events. Hence adhering with the guidelines we can achieve maximum clinical effect with minimum duration. Key words: DAPT, Myocardial infarction, ACS, Clopidogrel, Aspirin, Ticagrelor, PCI, Bleeding |
| Keywords: | DAPT, Myocardial infarction, ACS, Clopidogrel, Aspirin, Ticagrelor, PCI, Bleeding |
| Cite Article: | "UTILIZATION OF DUAL ANTIPLATELET THERAPY IN CARDIOVASCULAR DISEASE PATIENTS – A PROSPECTIVE OBSERVATIONAL STUDY", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 2, page no.228 - 240, February-2024, Available :http://www.ijrti.org/papers/IJRTI2402036.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2402036
Registration ID:189182
Published In: Volume 9 Issue 2, February-2024
DOI (Digital Object Identifier):
Page No: 228 - 240 Country: Bengaluru, Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2402036 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2402036 |
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ISSN: 2456-3315
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