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Paper Title
Advancement in Quantitative Analytical Method Development for Fluconazole: A Review
Authors
Prajwal khutale , Dr. Prasanna A. Datar , Prof.R. Sonawane , Varad Kalyan Kale , Rupali Ramesh Tawar
Keywords
Fluconazole, quantitative analysis, analytical methods, chromatography, spectrophotometry, electrochemistry, method validation.
Abstract
Fluconazole, a potent antifungal agent, holds significant therapeutic value in combating fungal
infections. Accurate quantification of fluconazole is paramount for ensuring proper dosage,
therapeutic efficacy, and quality control in pharmaceutical formulations. This comprehensive
review delves into the evolution of quantitative analytical techniques for fluconazole
determination, emphasizing methodological advancements, challenges, and future prospects.
Chromatographic methods, including high-performance liquid chromatography (HPLC), ultra
high-performance liquid chromatography (UHPLC), gas chromatography (GC), and capillary
electrophoresis (CE), alongside spectrophotometric and electrochemical approaches, are
scrutinized. Factors influencing method development, such as selectivity, sensitivity, accuracy,
precision, linearity, and robustness, are meticulously explored. Sample preparation techniques and
validation parameters are discussed to underscore their critical role in method optimization and
validation. Furthermore, recent innovations and emerging trends in fluconazole analysis are
elucidated, providing valuable insights for researchers and analysts in pharmaceutical and
analytical chemistry domains.
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How To Cite
"Advancement in Quantitative Analytical Method Development for Fluconazole: A Review", IJRTI - International Journal for Research Trends and Innovation (www.IJRTI.org), ISSN:2456-3315, Vol.9, Issue 6, page no.340 - 351, June-2024, Available :https://ijrti.org/papers/IJRTI2406045.pdf
Issue
Volume 9 Issue 6,
June-2024
Pages : 340 - 351
Other Publication Details
Paper Reg. ID: IJRTI_190033
Published Paper Id: IJRTI2406045
Downloads: 205,607
Research Area: Pharmacy
Country: Wardha, Maharashtra, India
Published Paper PDF: https://ijrti.org/papers/IJRTI2406045
Published Paper URL: https://ijrti.org/viewpaperforall?paper=IJRTI2406045
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ISSN: 2456-3315 | IMPACT FACTOR: 10.57 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 10.57 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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© 2024 — Authors hold the copyright of this article.
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