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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: April 2025
Volume 10 | Issue 4
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 107
Article Submitted : 13636
Article Published : 6402
Total Authors : 16956
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Total Countries : 116
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| Paper Title: | Assessing the Efficacy of Biodegradable PLA Dural Patches in Surgical Applications |
| Authors Name: | Minocha Dr. Pramodkumar , Kothwala Dr. Deveshkumar , Lodha Dikshita , Shukla Dhananjaya , Gandhi Jalesh, Desai Mansi |
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IJRTI_200610
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| Published Paper Id: | IJRTI2502053 |
| Published In: | Volume 10 Issue 2, February-2025 |
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| Abstract: | In this study, we demonstrated the manufacturing of a Dural Patch using a biodegradable polymer PLA Poly Lactic Acid (PLA), for use in neurosurgery. The focus of the study is on the manufacturing process, with particular attention to the compatibility and melting behavior of various components with PLA, as well as the techniques employed to achieve optimal integration. A series of experiments were carried out on the Patch to assess its biocompatibility, and its physical and mechanical qualities, which are crucial for its planned application in a clinical context. These assessments reveal that the PLA Patch has good mechanical qualities and biocompatibility and can be employed in surgery. Also, the present work discusses the Neurosurgical operation following implantation of the Patch in the topical tissues of the brain indicating its usefulness for postoperative problems, for instance, septic and CSF (Cerebro Spinal Fluid) leakage. The possible advantages include rapid patient recovery, and a lesser chance of issues connected to standard Patch biomaterials. Some benefits of adopting PLA-based materials in Dural healing are explored including their higher biodegradability and bio-absorbability compared to current plastic and biological alternatives. The results from the bench-scale study indicate promising performance of PLA Dural Patches. The findings highlight the PLA Dural Patch's robust mechanical properties and excellent biocompatibility, making it promising medical resolutions for neurosurgical applications. Its ability to reduce postoperative complications, coupled with the advantages of biodegradability and bio-absorbability, underscores its potential to improve patient outcomes in clinical solutions. |
| Keywords: | “Assessing the Efficacy of Biodegradable PLA Dural Patches in Surgical Applications” |
| Cite Article: | "Assessing the Efficacy of Biodegradable PLA Dural Patches in Surgical Applications ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 2, page no.a528-a538, February-2025, Available :http://www.ijrti.org/papers/IJRTI2502053.pdf |
| Downloads: | 000107 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2502053
Registration ID:200610
Published In: Volume 10 Issue 2, February-2025
DOI (Digital Object Identifier):
Page No: a528-a538 Country: -, -, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2502053 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2502053 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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