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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: March 2026
Volume 11 | Issue 3
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21604
Article Published : 8531
Total Authors : 22438
Total Reviewer : 805
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| Paper Title: | SUSTAINED RELEASE ANTIDIABETIC DRUG : A REVIEW |
| Authors Name: | NEERUDU SUPRIYA , JIMIDI BHASKAR , P SOWMYASRI |
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| Author Reg. ID: |
IJRTI_201150
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| Published Paper Id: | IJRTI2503063 |
| Published In: | Volume 10 Issue 3, March-2025 |
| DOI: | |
| Abstract: | The aim of this study was to design and evaluate a sustained-release formulation. a commonly used anti-diabetic medication, to improve patient compliance and reduce dosing frequency.sustained-release tablets were prepared using various polymers, including hydroxypropyl methylcellulose (HPMC), ethyl cellulose (EC), and polyvinyl pyrrolidone (PVP). The tablets were evaluated for their physicochemical properties, in vitro drug release, and in vivo pharmacokinetic performance. The optimized formulation showed a controlled release of over 24 hours, with a release exponent (n) indicating non-Fickian diffusion. In vivo studies demonstrated a significant reduction in blood glucose levels, with a prolonged hypoglycemic effect. The results suggest that the developed sustained-release formulation of has the potential to improve therapeutic outcomes and enhance patient compliance in the management of diabetes mellitus. |
| Keywords: | Sustained-release formulation, Anti-diabetic drug, Hydroxypropyl methylcellulose (HPMC), Ethyl cellulose (EC), Polyvinyl pyrrolidone (PVP), Diabetes mellitus, Pharmacokinetics, Controlled release |
| Cite Article: | "SUSTAINED RELEASE ANTIDIABETIC DRUG : A REVIEW ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 3, page no.a477-a490, March-2025, Available :http://www.ijrti.org/papers/IJRTI2503063.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2503063
Registration ID:201150
Published In: Volume 10 Issue 3, March-2025
DOI (Digital Object Identifier):
Page No: a477-a490 Country: Rangareddi, Telangana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2503063 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2503063 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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