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The aim of this research was to develop and evaluate an oral medicated jelly formulation of paracetamol tailored for pediatric use. Oral jellies provide an attractive alternative to traditional solid and liquid dosage forms, especially for children who often experience difficulty swallowing tablets or dislike the taste of syrups. In this study, paracetamol jellies were prepared using natural and synthetic gelling agents such as pectin, sodium alginate, and gelatin, in combination with sweeteners and flavoring agents to enhance palatability. The formulations were evaluated for physical appearance, viscosity, pH, drug content uniformity, in vitro drug release, and stability under various conditions. Among the various formulations, the jelly prepared using pectin exhibited optimal characteristics including pleasant taste, uniform drug distribution, and a controlled release profile suitable for pediatric administration. Stability studies confirmed that the jelly remained physically and chemically stable over a 3-month period. The results suggest that oral medicated jelly is a promising and patient-friendly dosage form for delivering paracetamol to children, improving compliance and therapeutic effectiveness.
" FORMULATION AND EVALUATION OF ORAL MEDICATED PARACETAMOL JELLY FOR PEDIATRICS ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.c119-c132, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504238.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator