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Abstract
Background: ABO and Rh blood groups may influence immune-mediated conditions including skin allergies.
AB-negative is an extremely rare phenotype and its relationship with dermatological hypersensitivity remains
underexplored.
Case Presentation: We report a 26-year-old AB-negative female with severe sensitive skin allergy, systemic
involvement including allergic rhinitis, atopic dermatitis, chronic dermatitis, and chronic spontaneous urticaria.
Cohort Analysis: In a small population sample (n=50, all Rh positive), only 3% exhibited similar allergic
responses to environmental triggers (dry weather, oily skin, stress).
Results: The index case had severe allergy (high score, 35–32 on severity scales). Among the Rh-positive
cohort, prevalence of skin allergy remained low (3%).
Conclusion: Rare AB-negative blood group may represent a higher-risk subgroup for skin allergy. Further
multicentric studies are warranted.
Keywords:
AB negative blood group and severe skin allergy: A case report and small cohort analysis
Cite Article:
"AB negative blood group and severe skin allergy ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 9, page no.b282-b284, September-2025, Available :http://www.ijrti.org/papers/IJRTI2509135.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator