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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: March 2026
Volume 11 | Issue 3
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21574
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Total Authors : 22430
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| Paper Title: | "Unraveling Rheumatoid Arthritis: Mechanisms, Management, and Future Frontiers" |
| Authors Name: | Samina Mujawar , vasim aparadh , vishakha Gurav , saniya mullani , neha gaikwad |
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IJRTI_208024
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| Published Paper Id: | IJRTI2511170 |
| Published In: | Volume 10 Issue 11, November-2025 |
| DOI: | |
| Abstract: | Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint destruction, bone and cartilage devastation, and rigidity, primarily affecting the elderly population and women. The disease is associated with an imbalance between autoimmune cells, resulting in systemic joint inflammation, chronic synovitis, and tissue destruction. With a prevalence of 1% in adults, RA ranks 42nd in terms of global disability and is linked to significant mortality rates, with 10-20% and 60-80% of deaths attributed to heart conditions and pulmonary problems, respectively. This review aims to provide an in-depth understanding of the molecular mechanisms underlying RA, including the role of major histocompatibility complex molecules and dependent T-cells. Furthermore, this study will examine the current treatment options and management strategies for RA, highlighting the need for a multi-faceted approach to mitigate the disease's systemic consequences and improve patient outcomes. By elucidating the complex interplay between autoimmune cells, inflammation, and tissue destruction, this research seeks to contribute to the development of effective therapeutic interventions for RA, ultimately reducing the burden of this debilitating disease on individuals and societies worldwide. |
| Keywords: | Rheumatoid arthrits ,arachidonic acid, synovium, TNF-α, citrullinated proteins |
| Cite Article: | ""Unraveling Rheumatoid Arthritis: Mechanisms, Management, and Future Frontiers"", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 11, page no.b605-b630, November-2025, Available :http://www.ijrti.org/papers/IJRTI2511170.pdf |
| Downloads: | 000185 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2511170
Registration ID:208024
Published In: Volume 10 Issue 11, November-2025
DOI (Digital Object Identifier):
Page No: b605-b630 Country: kagal,olhapur, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2511170 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2511170 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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