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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Volume 11 | Issue 2
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 117
Article Submitted : 21318
Article Published : 8476
Total Authors : 22301
Total Reviewer : 802
Total Countries : 156
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| Paper Title: | GENETIC AND EPIGENETIC FACTORS CONTRIBUTING TO THE DEVELOPMENT OF PCOD |
| Authors Name: | Rupali Jadhao , Ashvini Nagare |
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| Author Reg. ID: |
IJRTI_208469
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| Published Paper Id: | IJRTI2512072 |
| Published In: | Volume 10 Issue 12, December-2025 |
| DOI: | |
| Abstract: | Polycystic Ovarian Disease (PCOD) is a common endocrine and metabolic disorder affecting women of reproductive age. It is characterized by chronic anovulation, hyperandrogenism, and polycystic ovarian morphology. The etiology of PCOD is complex and multifactorial, involving genetic predisposition, hormonal imbalance, insulin resistance, obesity, and environmental influences. Studies show that 40–70% of women with PCOD have a family history of metabolic or reproductive disorders, highlighting a strong genetic component. Epigenetic changes caused by lifestyle, diet, stress, and endocrine-disrupting chemicals may alter gene expression and contribute to disease progression. Understanding the interaction between genetic and environmental factors is essential for improving diagnosis and individualized treatment. This review summarizes the mechanisms, risk factors, clinical features, and current approaches for managing PCOD. To review the genetic, epigenetic, hormonal, and environmental factors involved in the development of PCOD and summarize current trends in diagnosis and management. |
| Keywords: | PCOD, PCOS, Hyperandrogenism, Insulin resistance, Ovarian dysfunction, Anovulation, Hormonal imbalance, Genetics, Epigenetics. |
| Cite Article: | "GENETIC AND EPIGENETIC FACTORS CONTRIBUTING TO THE DEVELOPMENT OF PCOD", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 12, page no.a569-a573, December-2025, Available :http://www.ijrti.org/papers/IJRTI2512072.pdf |
| Downloads: | 000171 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2512072
Registration ID:208469
Published In: Volume 10 Issue 12, December-2025
DOI (Digital Object Identifier):
Page No: a569-a573 Country: pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2512072 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2512072 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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