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Abstract: Metal-organic frameworks have rapidly gained popularity as a new type of material that combines organic linkers with metal ions. This huge family is becoming increasingly attractive for drug delivery due to their tunable porosity, chemical composition, size and form, and ease of surface functionalization. Over the last few decades, there has been an increasing interest in the development of tailored MOFs with regulated sizes for a range of biomedical applications. This article presents overall review and perspectives of MOFs-based drug delivery systems (DDSs). This article starting with the different strategies for synthesis of MOFs along with different factor that affect the synthesis. Then different general characterization techniques and nomenclature procedure also discuss. As the MOFs have wide range of application, we cover most important application like imaging, sensing, gas storage, separation catalysis, magnetism and biomedical application. After disusing the broadness of MOFs, we delegate our focus on different properties and functionalization for drug delivery. Procedures of drug loading on MOFs are also important so it is explained. Lastly, we classified the MOFs based on specific metal ion and organic ligand on account of drug delivery; with end of the section different therapeutic applications are explained.
Keywords:
MOFs, Bio-MOFs, drug loading, drug delivery system, synthesis method, characterization technique, bio- compatibility, Diseases therapy, bio-medical application
Cite Article:
"Metal Organic Frameworks as Emerging Carriers for Drug Delivery: A Review", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 4, page no.a219-a267, April-2026, Available :http://www.ijrti.org/papers/IJRTITH06009.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator