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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21544
Article Published : 8519
Total Authors : 22414
Total Reviewer : 805
Total Countries : 159
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| Paper Title: | Features and Facts of Gastro-retentive Drug Delivery System: A Review |
| Authors Name: | Pratiksha Tukaram Bhalekar , Dr. Uday A. Deokate , Manjari N. Bobde |
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IJRTI_183460
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| Published Paper Id: | IJRTI2208032 |
| Published In: | Volume 7 Issue 8, August-2022 |
| DOI: | |
| Abstract: | Gastro-retentive Drug Delivery System (GRDDS) is one of the achievable and appreciable approaches in controlled release drug delivery systems. These systems overcome several limitations regarding the oral drug delivery system. Various limitations which vary from patient to patient or may also vary from drug to drug. However, the therapeutic efficacy and bioavailability of therapeutic agents are laid on the retention time of within the targeted site. Hence, GRDDS enhances bioavailability by increasing residence time in the stomach along with showing targeted action within stomach as well as in the upper small intestinal window without affecting gastric emptying time. Bioavailability can be enhanced, especially for those drug candidates which have narrow absorption windows, shorter half-life, are unstable at alkaline pH, etc. Thus, GRDDS comprises of different classes of systems which act through different ways of action including Effervescent systems. Floating systems. Raft forming systems. Ion exchangeable resins. High density systems etc. Today, GRDDS has earned a wide range of opportunities and scope in the market comparatively conventional dosage forms. |
| Keywords: | Gastro- retentive Drug Delivery system, Bioavailability, Gastric Retention time, Various Approaches. |
| Cite Article: | "Features and Facts of Gastro-retentive Drug Delivery System: A Review", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 8, page no.193 - 205, August-2022, Available :http://www.ijrti.org/papers/IJRTI2208032.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2208032
Registration ID:183460
Published In: Volume 7 Issue 8, August-2022
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Page No: 193 - 205 Country: Aurangabad, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2208032 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2208032 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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