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Solubility is the phenomenon of dissolution of solids in the liquid phase to give a homogeneous system . Solubility is one of the parameters to achieve the desired concentration of drug in systemic circulation for pharmacology response to be shown. Prooly water soluble drugs often require high doses to reach therapeutic plasma concentration after oral administration. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities. The solubility is the most important concept presenting itself as a variable contributor in the formulation of pharmaceuticals. The usable pharmaceuticals with poor solubility means be answered well by solubilization techniques such as chemical modification which involves the use of solubilizer such as physical modification complexation use of surfactant. The purpose of the review article is to describe the techniques of solubilization for attainment of effective absorption and improved bioavailability
"A Review on Solubility Enhancement Techniques ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 10, page no.143 - 155, October-2023, Available :http://www.ijrti.org/papers/IJRTI2310022.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator