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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 114
Article Submitted : 18650
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Total Authors : 20781
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| Paper Title: | A risk-based industrial approach to the formulation and optimization of liquid crystalline nanoparticles (LCNPs) using quality by design (QbD) |
| Authors Name: | Punam V. Wankhade , Vinayak A. Katekar , Dr. Swati Deshmukh |
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IJRTI_188906
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| Published Paper Id: | IJRTI2401009 |
| Published In: | Volume 9 Issue 1, January-2024 |
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| Abstract: | Lipid-based lyotropic liquid crystals, also called “liquid crystalline nanoparticles” (LCNPs), are a new type of nanocarrier systems that arise from the combination of lyotropic liquid crystals and lipid-based nanoparticles. The special benefits and enormous popularity of LCNPs can be better utilized. One systematic approach that can be used in formulation development is QbD. Applying QbD to the formulation of LCNPs will offer several distinct benefits, including improved understanding of the product and process, process flexibility within the design space, application of more effective and efficient control strategies, simple transfer from bench to bedside, and more robust product. The use of QbD in the formulation of LCNPs has been investigated in this work.Case studies have been used to provide a thorough explanation of each of the QbD components, which include the quality target product profile, critical quality attributes, critical material attributes, critical process parameters, quality risk management, experiment design, and control strategy for the production of LCNPs. The current study will give the reader a foundation for QbD-driven formulation of LCNPs from a regulatory perspective and assist them in understanding the specifics of applying QbD to the formulation of LCNPs |
| Keywords: | Liquid crystalline nanoparticles Quality by design ,Relative risk-based matrix analysis , Quality risk management , Design of experiments |
| Cite Article: | "A risk-based industrial approach to the formulation and optimization of liquid crystalline nanoparticles (LCNPs) using quality by design (QbD)", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 1, page no.49 - 57, January-2024, Available :http://www.ijrti.org/papers/IJRTI2401009.pdf |
| Downloads: | 000205194 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2401009
Registration ID:188906
Published In: Volume 9 Issue 1, January-2024
DOI (Digital Object Identifier):
Page No: 49 - 57 Country: -, -, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2401009 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2401009 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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