ISSN2456-3315
Impact Factor10.57
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CrossRefDOI
ESTD2016
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AccessOpen
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Paper Title
Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form.
Authors
Kedar Tejashree R , Jadhav Ankush P , Kore Kakasaheb J. , Jadhav Ravindra T.
Keywords
Paracetamol, Ibuprofen, Simultaneous equation, Absorbance ratio, Validation.
Abstract
Two simple, rapid, accurate, precise, and economic spectrophotometric methods for simultaneous estimation of paracetamol and ibuprofen in pure and tablet dosage form have been developed. Method I is based on the simultaneous equation method. Paracetamol and ibuprofen show absorbance maximums at 256 and 222.4 nm respectively, so absorbance was measured at the same wave lengths for the estimation of paracetamol and ibuprofen. Method II is based on determination of Q-value. Absorbance is measured at 226.4 nm (Isoabsorptive point) and 222.4nm (λmax of ibuprofen). Both drugs obey the Beer Lambert's law in the concentration range of 5-30 µg/mL. Methods are validated according to ICH guidelines.
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IJRTI — journal style
"Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form.", IJRTI - International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.5, Issue 5, page no.116 - 121, May-2020, Available :https://ijrti.org/papers/IJRTI2005019.pdf
APA — 7th edition
R, K. T., P, J. A., J., K. K., & T., J. R. (2020). Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form. International Journal for Research Trends and Innovation, 5(5), 116 - 121. https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019
MLA — 9th edition
R, Kedar Tejashree, et al. "Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form." International Journal for Research Trends and Innovation, vol. 5, no. 5, 2020, pp. 116 - 121, https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019.
Chicago — 17th, bibliography
R, Kedar Tejashree, et al. "Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form." International Journal for Research Trends and Innovation 5, no. 5 (2020): 116 - 121. https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019.
Harvard — author–date
R, K.T. et al. (2020) 'Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form', International Journal for Research Trends and Innovation, 5(5), pp. 116 - 121. Available at: https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019
IEEE — numbered reference
K. T. R, J. A. P, K. K. J. and J. R. T., "Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form," IJRTI, vol. 5, no. 5, pp. 116 - 121, May. 2020.
Vancouver — biomedical
R KT, P JA, J. KK, T. JR. Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form. IJRTI. 2020 May;5(5):116 - 121.
AMA — 11th edition
R KT, P JA, J. KK, T. JR. Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form. IJRTI. 2020;5(5):116 - 121. Accessed at https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019
BibTeX — Zotero, Mendeley, LaTeX
@article{IJRTI2005019,
author = {Kedar Tejashree R and Jadhav Ankush P and Kore Kakasaheb J. and Jadhav Ravindra T.},
title = {Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form.},
journal = {International Journal for Research Trends and Innovation},
volume = {5},
number = {5},
pages = {116 - 121},
year = {2020},
month = {May},
issn = {2456-3315},
url = {https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - R, Kedar Tejashree
AU - P, Jadhav Ankush
AU - J., Kore Kakasaheb
AU - T., Jadhav Ravindra
TI - Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form.
T2 - International Journal for Research Trends and Innovation
JA - IJRTI
VL - 5
IS - 5
PY - 2020
SN - 2456-3315
UR - https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019
SP - 116
EP - 121
ER -
Issue
Volume 5 Issue 5,
May-2020
Pages : 116 - 121
Other Publication Details
Paper Reg. ID
IJRTI_181264
Published Paper ID
IJRTI2005019
Downloads
205,660
Research Area
Pharmacy
Country
Pune, Maharashtra, India
Published
May 2020
Published Paper PDF
https://ijrti.org/papers/IJRTI2005019.pdf
Published Paper URL
https://ijrti.org/viewpaperforall.php?paper=IJRTI2005019
About Publisher
International Journal for Research Trends and Innovation
Published by IJRTI (JW Publication)
2456-3315
ISSN
10.57
Impact Factor
2016
ESTD Year
Open
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Impact Factor 10.57 calculated by Google Scholar and Semantic Scholar.
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Declarations
Funding
No external funding was received for this study.
Conflict of Interest
The authors declare that they have no conflict of interest.
Acknowledgements
The authors would like to thank the reviewers and the editorial board of International Journal for Research Trends and Innovation for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.
