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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Volume 10 | Issue 5
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 108
Article Submitted : 15058
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| Paper Title: | Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form. |
| Authors Name: | Kedar Tejashree R , Jadhav Ankush P , Kore Kakasaheb J. , Jadhav Ravindra T. |
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IJRTI_181264
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| Published Paper Id: | IJRTI2005019 |
| Published In: | Volume 5 Issue 5, May-2020 |
| DOI: | |
| Abstract: | Two simple, rapid, accurate, precise, and economic spectrophotometric methods for simultaneous estimation of paracetamol and ibuprofen in pure and tablet dosage form have been developed. Method I is based on the simultaneous equation method. Paracetamol and ibuprofen show absorbance maximums at 256 and 222.4 nm respectively, so absorbance was measured at the same wave lengths for the estimation of paracetamol and ibuprofen. Method II is based on determination of Q-value. Absorbance is measured at 226.4 nm (Isoabsorptive point) and 222.4nm (λmax of ibuprofen). Both drugs obey the Beer Lambert's law in the concentration range of 5-30 µg/mL. Methods are validated according to ICH guidelines. |
| Keywords: | Paracetamol, Ibuprofen, Simultaneous equation, Absorbance ratio, Validation. |
| Cite Article: | "Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in bulk and tablet dosage form. ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 5, page no.116 - 121, May-2020, Available :http://www.ijrti.org/papers/IJRTI2005019.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2005019
Registration ID:181264
Published In: Volume 5 Issue 5, May-2020
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Page No: 116 - 121 Country: Pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2005019 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2005019 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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