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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | PHYTOCHEMICAL SCREENING OF CYAMOPSIS TETRAGONOLOBA L. EXTRACTS |
| Authors Name: | Dr. Shrinivas K Sarje , Seema Bhalerao , Dinesh Shinde , Mahima Katariya , Shagufta Farooqui |
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IJRTI_181347
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| Published Paper Id: | IJRTI2009005 |
| Published In: | Volume 5 Issue 9, September-2020 |
| DOI: | |
| Abstract: | Medicinal plants have always been the principle sources of medicine worldwide. Human beings have used those as medicine from the very beginning of time. India sustains a very rich traditional medicinal plant wealth and inherits unique plant and animal communities. The objective of the study was undertaken to investigate the hepatoprotective activity of Ethyl Acetate & Methanolic extract of Cyamopsis tetragonoloba L. pods which is an important medicinal plant in Indian folk. In the present study the pods of Cyamopsis tetragonoloba which belongs to family Fabaceae were chosen because various parts of the plant possesses several bioactivities & is used in traditional medicinal system. The pods of Cyamopsis tetragonoloba L. were collected, processed & standardized as per official methods. Two extracts of Cyamopsis tetragonoloba L. pods (Ethyl Acetate and Methanolic) were studied to detect the chemical compounds present, to evaluate acute oral toxicity & hepatoprotective activity. Qualitative phytochemical screening revealed the presence of flavonoid, p-coumarin, Saponins, tannin and triterpenes. Total Polyphenol content & total flavonoid content was determined by Folin Ciocaltue & Aluminium trichloride method respectively by using UV-Visible spectrophotometer. Physical parameters like solubility, ash values, LOD, extractive value etc. has been studied. The antioxidant activity of the extracts was done by using DPPH method. The results showed that Ethyl Acetate extract and Methanolic extract at 125μg/ml concentration showed the significant antioxidant effect as compared with ascorbic acid as standard. The In-vivo hepatoprotective activity of C.T.EA and C.T.Mth extracts were estimated by using carbon tetrachloride induced hepatotoxicity model. The degree of protection was estimated by measuring levels of biochemical markers like SGOT, SGPT, Total Bilirubin and Total Protein. The histopathological study was also carried sout and compared with carbon tetrachloride treated group. |
| Keywords: | Cyamopsis tetragonoloba L. (C.T.) Ethyl Acetate (EA) and Methanolic (Mth.) extracts, Phytochemical screening, Antioxidant activity, Hepatoprotective activity. |
| Cite Article: | "PHYTOCHEMICAL SCREENING OF CYAMOPSIS TETRAGONOLOBA L. EXTRACTS ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 9, page no.41 - 48, September-2020, Available :http://www.ijrti.org/papers/IJRTI2009005.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2009005
Registration ID:181347
Published In: Volume 5 Issue 9, September-2020
DOI (Digital Object Identifier):
Page No: 41 - 48 Country: Nanded, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2009005 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2009005 |
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ISSN: 2456-3315
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