ISSN2456-3315
Impact Factor10.57
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ESTD2016
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Paper Title
A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM
Authors
Firdos Habeeb , Dr. Shahid Mohammed
Keywords
Pulsatile Drug Delivery System, chronopharmacotherapy Time-controlled Drug Delivery System, Circadian rhythm, Lag time.
Abstract
Pulsatile drug delivery systems are developed to deliver drug according to circadian behavior of diseases. The product follow a sigmoidal drug release profile characterized by a time period of no release (lag time) followed by a rapid and complete drug release. Thus drug can be delivered at right time, in right amount and at right site of action by use of such approach. A pulse must be planned so that a complete and rapid medication release is accomplished after the lag time. Pulsatile drug delivery system (PDDS) delivers the drug at specific time as per the patho-physiological need of the disease, resulting in improved therapeutic efficacy and patient compliance. Diseases wherein PDDS are promising include asthma, peptic ulcer, cardiovascular diseases, arthritis, attention deficit syndrome in children, and hypercholesterolemia. Various technologies such as time-controlled, pulsed, triggered and programmed drug delivery devices have been developed and extensively studied in recent years for chronopharmaceutical drug delivery. These systems are beneficial for diseases showing chronopharmacological behavior where night time dosing is required or for the drugs having high first pass effect or having site specific absorption in GIT, or for drugs with high risk of toxicity or tolerance. These systems also improve patient compliance by decreasing dosing frequency.
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IJRTI — journal style
"A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM", IJRTI - International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.6, Issue 9, page no.124 - 136, September-2021, Available :https://ijrti.org/papers/IJRTI2109020.pdf
APA — 7th edition
Habeeb, F., & Mohammed, S. (2021). A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM. International Journal for Research Trends and Innovation, 6(9), 124 - 136. https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020
MLA — 9th edition
Habeeb, Firdos, and Shahid Mohammed. "A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM." International Journal for Research Trends and Innovation, vol. 6, no. 9, 2021, pp. 124 - 136, https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020.
Chicago — 17th, bibliography
Habeeb, Firdos, and Shahid Mohammed. "A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM." International Journal for Research Trends and Innovation 6, no. 9 (2021): 124 - 136. https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020.
Harvard — author–date
Habeeb, F. and Mohammed, S. (2021) 'A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM', International Journal for Research Trends and Innovation, 6(9), pp. 124 - 136. Available at: https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020
IEEE — numbered reference
F. Habeeb and S. Mohammed, "A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM," IJRTI, vol. 6, no. 9, pp. 124 - 136, Sep. 2021.
Vancouver — biomedical
Habeeb F, Mohammed S. A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM. IJRTI. 2021 Sep;6(9):124 - 136.
AMA — 11th edition
Habeeb F, Mohammed S. A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM. IJRTI. 2021;6(9):124 - 136. Accessed at https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020
BibTeX — Zotero, Mendeley, LaTeX
@article{IJRTI2109020,
author = {Firdos Habeeb and Shahid Mohammed},
title = {A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM},
journal = {International Journal for Research Trends and Innovation},
volume = {6},
number = {9},
pages = {124 - 136},
year = {2021},
month = {September},
issn = {2456-3315},
url = {https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Habeeb, Firdos
AU - Mohammed, Shahid
TI - A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM
T2 - International Journal for Research Trends and Innovation
JA - IJRTI
VL - 6
IS - 9
PY - 2021
SN - 2456-3315
UR - https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020
SP - 124
EP - 136
ER -
Issue
Volume 6 Issue 9,
September-2021
Pages : 124 - 136
Other Publication Details
Paper Reg. ID
IJRTI_181623
Published Paper ID
IJRTI2109020
Downloads
205,601
Research Area
Pharmacy
Country
Hyderabad, Telengana , India
Published
September 2021
Published Paper PDF
https://ijrti.org/papers/IJRTI2109020.pdf
Published Paper URL
https://ijrti.org/viewpaperforall.php?paper=IJRTI2109020
About Publisher
International Journal for Research Trends and Innovation
Published by IJRTI (JW Publication)
2456-3315
ISSN
10.57
Impact Factor
2016
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Open
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Impact Factor 10.57 calculated by Google Scholar and Semantic Scholar.
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Declarations
Funding
No external funding was received for this study.
Conflict of Interest
The authors declare that they have no conflict of interest.
Acknowledgements
The authors would like to thank the reviewers and the editorial board of International Journal for Research Trends and Innovation for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.
