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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM |
| Authors Name: | Firdos Habeeb , Dr. Shahid Mohammed |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_181623
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| Published Paper Id: | IJRTI2109020 |
| Published In: | Volume 6 Issue 9, September-2021 |
| DOI: | |
| Abstract: | Pulsatile drug delivery systems are developed to deliver drug according to circadian behavior of diseases. The product follow a sigmoidal drug release profile characterized by a time period of no release (lag time) followed by a rapid and complete drug release. Thus drug can be delivered at right time, in right amount and at right site of action by use of such approach. A pulse must be planned so that a complete and rapid medication release is accomplished after the lag time. Pulsatile drug delivery system (PDDS) delivers the drug at specific time as per the patho-physiological need of the disease, resulting in improved therapeutic efficacy and patient compliance. Diseases wherein PDDS are promising include asthma, peptic ulcer, cardiovascular diseases, arthritis, attention deficit syndrome in children, and hypercholesterolemia. Various technologies such as time-controlled, pulsed, triggered and programmed drug delivery devices have been developed and extensively studied in recent years for chronopharmaceutical drug delivery. These systems are beneficial for diseases showing chronopharmacological behavior where night time dosing is required or for the drugs having high first pass effect or having site specific absorption in GIT, or for drugs with high risk of toxicity or tolerance. These systems also improve patient compliance by decreasing dosing frequency. |
| Keywords: | Pulsatile Drug Delivery System, chronopharmacotherapy Time-controlled Drug Delivery System, Circadian rhythm, Lag time. |
| Cite Article: | "A REVIEW ON PULSATILE DRUG DELIVERY SYSTEM", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.6, Issue 9, page no.124 - 136, September-2021, Available :http://www.ijrti.org/papers/IJRTI2109020.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2109020
Registration ID:181623
Published In: Volume 6 Issue 9, September-2021
DOI (Digital Object Identifier):
Page No: 124 - 136 Country: Hyderabad, Telengana , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2109020 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2109020 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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