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Background: High-alert medications can also be defined as those medications which causes the highest risk of injury when misused, either due to a slim therapeutic window or to previous serious adverse events which was reported. These medications are not always the medications that most frequently lead to adverse events, but when not used as intended, these medications have the most serious consequences. The primary objective of the study is to identify and to measure the usage pattern of HAMs prescription and also to measure the combination therapy of HAMs in different age groups.
Method: The data collected from HICU. Patient case sheet with at least one high risk medications is analyzed and data has been collected based on inclusion criteria. Usage pattern of high-risk medication in different age groups is identified. Storing and labelling of HAMs in HICU is observed.
Result: A total of 65 prescription were analyzed in which males 41(63%) and females 24(37%) which shows the males were dominating over female patients. After analyzing the 65 prescriptions total of 140 HAMs were obtained, in that insulin 29(21%) was found to be highest scale followed by heparin 24(17%) and bisoprolol 23(16%). Considering the different age groups of patients, old adults/geriatrics (60-99 years) were the highest in numbers (54%) and followed by young adults (20-39 years) age groups. Combination therapy of Midazolam and Fentanyl is observed commonly. Almost 10% of patients were organ impairment in which renal impairment patients were maximum in numbers. Six DDI and two ADRs was also analyzed. Around 63% of patients are prescribe with LASA drugs.
Conclusion: In the study, the most frequently used HAM was found to be insulin29(21%) followed by heparin 24(17%) and Bisoprolol 23(16%). Males’ patients are predominating over females where males 41(63%) and females 24(37%). Diabetes mellitus, hypertension and bed ridden patients in the HICU are the reason for prescribing HAMs in this study. Six DDI and two ADRs also identified.
Keywords:
High alert medications (HAMs), ISMP (Institute for safe medicines practices, ADRs (adverse drug reactions), MEs (medication errors), DDI (drug-drug interactions)
Cite Article:
"A prospective, observational study on identification and measurement of Usage pattern of High-risk medication in High- Intensive Care Unit (HICU)", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 7, page no.371 - 377, July-2023, Available :http://www.ijrti.org/papers/IJRTI2307056.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator