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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Prevalence of Candida Species In A Tertiary Care Hospital And Its Invitro Antifungal Susceptibility Pattern Against Allium Sativum In Comparison With Antifungal Drugs |
| Authors Name: | J R Lilly Grace , Dr.G.Bhuvaneshwari , Dr. P NEELUSREE |
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IJRTI_187582
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| Published Paper Id: | IJRTI2307058 |
| Published In: | Volume 8 Issue 7, July-2023 |
| DOI: | |
| Abstract: | Allicin is one of the main components of fresh and crushed garlic with a varied range of effects, including genotoxic, antiapoptotic, antimicrobial, antiviral, antifungal, antiparasitic properties. Accordingly, this component entails antifungal properties against C.albicans. Garlic compounds are divided into two major groups of sulphur containing and non-sulphur-containing. (1) Thus this study aims to check the cell membrane activity of garlic against Candida species.Out of 71 samples, Candida albicans were isolated from 17 (24%) samples. The remaining 54 (66%) were Candida non-albicans. The zone of inhibition of growth in SDA was measured. Scanning electron microscopy investigation indicated loss of structural integrity. This showed that the extract of garlic was found to be effective against different Candida spp strain. Candida treated with garlic extract had rough and fluffy surface and also irregularly-shape. Based on the work, the effectiveness of garlic was determined and the mechanism of susceptibility was identified. With future research works in the field, many such natural herbal extracts can be proven to be effective against many pathogenic fungal infections. The antifungal susceptibility test should be done to every isolates in order to rule out the amphotericin B, other azole drug resistance and also the resistance of Allium sativum in order to help in the treatment by equipping clinician with herbal antifungal drugs. |
| Keywords: | Candida Spp, SEM, MIC, Allium sativum, Antifungal susceptibility testing |
| Cite Article: | "Prevalence of Candida Species In A Tertiary Care Hospital And Its Invitro Antifungal Susceptibility Pattern Against Allium Sativum In Comparison With Antifungal Drugs", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 7, page no.383 - 387, July-2023, Available :http://www.ijrti.org/papers/IJRTI2307058.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2307058
Registration ID:187582
Published In: Volume 8 Issue 7, July-2023
DOI (Digital Object Identifier):
Page No: 383 - 387 Country: CHENNAI, TAMIL NADU, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2307058 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2307058 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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