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Paper Title
Evaluation of Hepatoprotective Potential of Ethanol Extract From Black Resin Fruit In Nsaids-Induced Hepatotoxicity In Rats
Authors
Shraddha.R.Wasnik , Amol Bondre , Poonam Bihone , Rajesh Mujariya , Manjeet Singh
Keywords
Biochemical parameters, Hepatoprotective, Alcoholic Liver Diseases (ALD), Ethanol
Abstract
Hepatoprotective activity of the ethanolic of black resin was studied in Wistar rats using the ethanol-induced liver hepatotoxicty. Ethanol administration resulted in significant elevation of physical parameters (Viz. rat liver weight and liver volume), biochemical parameters like (Viz. serum aspirate transaminase (AST); alanine transminase (ALT); alkaline phasphatase (ALP); direct bilirubin and total bilirubin levels, while albumin and total protein were found to be decreased compared to normal group). Pretreatment with silymarin, ethanolic extract of Vitis vinifera significantly prevented the physical and biochemical changes induced by these hepatotoxins. Histopathology of liver confirmed our finding as the treatment with the extracts resulted in minor liver cell damage compared to toxic control group.
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How To Cite
"Evaluation of Hepatoprotective Potential of Ethanol Extract From Black Resin Fruit In Nsaids-Induced Hepatotoxicity In Rats", IJRTI - International Journal for Research Trends and Innovation (www.IJRTI.org), ISSN:2456-3315, Vol.9, Issue 6, page no.296 - 317, June-2024, Available :https://ijrti.org/papers/IJRTI2406042.pdf
Issue
Volume 9 Issue 6,
June-2024
Pages : 296 - 317
Other Publication Details
Paper Reg. ID: IJRTI_190026
Published Paper Id: IJRTI2406042
Downloads: 205,602
Research Area: Pharmacy
Country: -, -, India
Published Paper PDF: https://ijrti.org/papers/IJRTI2406042
Published Paper URL: https://ijrti.org/viewpaperforall?paper=IJRTI2406042
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ISSN: 2456-3315 | IMPACT FACTOR: 10.57 Calculated By Google Scholar | ESTD YEAR: 2016
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