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Hepatoprotective activity of the ethanolic of black resin was studied in Wistar rats using the ethanol-induced liver hepatotoxicty. Ethanol administration resulted in significant elevation of physical parameters (Viz. rat liver weight and liver volume), biochemical parameters like (Viz. serum aspirate transaminase (AST); alanine transminase (ALT); alkaline phasphatase (ALP); direct bilirubin and total bilirubin levels, while albumin and total protein were found to be decreased compared to normal group). Pretreatment with silymarin, ethanolic extract of Vitis vinifera significantly prevented the physical and biochemical changes induced by these hepatotoxins. Histopathology of liver confirmed our finding as the treatment with the extracts resulted in minor liver cell damage compared to toxic control group.
"Evaluation of Hepatoprotective Potential of Ethanol Extract From Black Resin Fruit In Nsaids-Induced Hepatotoxicity In Rats", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 6, page no.296 - 317, June-2024, Available :http://www.ijrti.org/papers/IJRTI2406042.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator