ISSN2456-3315
Impact Factor10.57
UGC CAREApproved
Low Cost₹599 / $45
CrossRefDOI
ESTD2016
Peer ReviewTransparent
AccessOpen
Submission: Always Open
Paper Title
DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE
Authors
Monali T. Dhapate , Manoj Shirbhate
Keywords
XRD, Drug, floating drug delivery systems, gastric residence time
Abstract
The purpose of this investigation was to prepare a floating drug delivery system of famotidine. Famotidine having poor absorption in acidic environment (upper GIT). When given orally, it shows the bioavailability near to 50%. To overcome these drawbacks, the present study was undertaken to investigate the floating dosage form of famotidine. The prepared tablets were evaluated for content uniformity, hardness, friability, buoyancy, swelling index and in-vitro dissolution studies. Further selected formulation was subjected for short term stability studies for one and two month at temperature of 25°c and 40°c respectively.XRD graph of pure 5-Fluorouracil drug. It is concluded that drug was crystalline in nature due to the sharpness in peak height. Sharpness in peaks was decreased in microspheres that indicated drug in the both the formulation goes to the amorphous nature which can enhance bioavailability.SEM showed that microspheres of drug with ethyl cellulose and eudragit RS 100 were smooth and porous almost spherical microspheres. The rough surface which may be due to presence of drug crystals on the surface of microspheres.
Full Paper, Downloads & Preview
How To Cite
Choose the style your journal or department asks for, then copy it. Every version below is generated from this paper's own record.
IJRTI — journal style
"DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE", IJRTI - International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.9, Issue 7, page no.149 - 159, July-2024, Available :https://ijrti.org/papers/IJRTI2407015.pdf
APA — 7th edition
Dhapate, M. T., & Shirbhate, M. (2024). DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE. International Journal for Research Trends and Innovation, 9(7), 149 - 159. https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015
MLA — 9th edition
Dhapate, Monali T., and Manoj Shirbhate. "DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE." International Journal for Research Trends and Innovation, vol. 9, no. 7, 2024, pp. 149 - 159, https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015.
Chicago — 17th, bibliography
Dhapate, Monali T., and Manoj Shirbhate. "DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE." International Journal for Research Trends and Innovation 9, no. 7 (2024): 149 - 159. https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015.
Harvard — author–date
Dhapate, M.T. and Shirbhate, M. (2024) 'DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE', International Journal for Research Trends and Innovation, 9(7), pp. 149 - 159. Available at: https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015
IEEE — numbered reference
M. T. Dhapate and M. Shirbhate, "DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE," IJRTI, vol. 9, no. 7, pp. 149 - 159, Jul. 2024.
Vancouver — biomedical
Dhapate MT, Shirbhate M. DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE. IJRTI. 2024 Jul;9(7):149 - 159.
AMA — 11th edition
Dhapate MT, Shirbhate M. DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE. IJRTI. 2024;9(7):149 - 159. Accessed at https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015
BibTeX — Zotero, Mendeley, LaTeX
@article{IJRTI2407015,
author = {Monali T. Dhapate and Manoj Shirbhate},
title = {DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE},
journal = {International Journal for Research Trends and Innovation},
volume = {9},
number = {7},
pages = {149 - 159},
year = {2024},
month = {July},
issn = {2456-3315},
url = {https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Dhapate, Monali T.
AU - Shirbhate, Manoj
TI - DESIGN AND DEVLOPMNT OF FLOATING DRUG DELIVERY SYSTEM OF FAMOTIDINE
T2 - International Journal for Research Trends and Innovation
JA - IJRTI
VL - 9
IS - 7
PY - 2024
SN - 2456-3315
UR - https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015
SP - 149
EP - 159
ER -
Issue
Volume 9 Issue 7,
July-2024
Pages : 149 - 159
Other Publication Details
Paper Reg. ID
IJRTI_190115
Published Paper ID
IJRTI2407015
Downloads
205,650
Research Area
Other
Country
-, -, India
Published
July 2024
Published Paper PDF
https://ijrti.org/papers/IJRTI2407015.pdf
Published Paper URL
https://ijrti.org/viewpaperforall.php?paper=IJRTI2407015
About Publisher
International Journal for Research Trends and Innovation
Published by IJRTI (JW Publication)
2456-3315
ISSN
10.57
Impact Factor
2016
ESTD Year
Open
Access
Impact Factor 10.57 calculated by Google Scholar and Semantic Scholar.
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 10.57 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
UGC CARE Approved Journal — Transparent Peer-reviewed journal aligned with UGC’s 2025 suggestive parameters, with CrossRef DOI registration and Scopus Standard metadata on every published paper.
Licence
© 2024 — Authors hold the copyright of this article.
This work is licensed under a
Creative Commons Attribution 4.0 International License
and The Open Definition.
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0),
which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Disclaimer:
The content, data and findings in this article are based on the authors’ research and have been
peer-reviewed for academic purposes only. Readers are advised to verify all information before practical
or commercial use. The journal and its editorial board are not liable for any errors, losses or
consequences arising from its use.
Declarations
Funding
No external funding was received for this study.
Conflict of Interest
The authors declare that they have no conflict of interest.
Acknowledgements
The authors would like to thank the reviewers and the editorial board of International Journal for Research Trends and Innovation for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.
