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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

Volume Published : 10

Issue Published : 115

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Paper Title: Targeting Oncogenes and Tumour Suppressor Genes with CRISPR
Authors Name: Rachel George
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IJRTI_201876
Published Paper Id: IJRTI2503241
Published In: Volume 10 Issue 3, March-2025
DOI:
Abstract: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized gene editing, offering unprecedented precision in targeting specific genes. This technology holds immense potential in cancer therapy by enabling the direct modification of oncogenes and tumour suppressor genes. When mutated or overexpressed, oncogenes drive cancer progression, while tumour suppressor genes, when inactivated, lose their ability to regulate cell proliferation. CRISPR-based genome editing provides a strategy to correct or knock out these genes, offering novel therapeutic approaches. This paper explores the latest advancements in CRISPR technology for targeting oncogenes and tumour suppressor genes, discussing its implications, methodologies, and outcomes in preclinical and clinical settings. We also analyse the challenges and ethical concerns associated with CRISPR-based gene therapies. By examining recent literature and experimental data, this paper aims to provide a comprehensive understanding of CRISPR’s role in cancer treatment and its future potential.
Keywords: CRISPR, Oncogenes, Tumour Suppressor Genes, Gene Therapy, Cancer Treatment, Genome Editing
Cite Article: "Targeting Oncogenes and Tumour Suppressor Genes with CRISPR", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 3, page no.c278-c281, March-2025, Available :http://www.ijrti.org/papers/IJRTI2503241.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2503241
Registration ID:201876
Published In: Volume 10 Issue 3, March-2025
DOI (Digital Object Identifier):
Page No: c278-c281
Country: BANGALORE, Karnataka, India
Research Area: Science & Technology
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2503241
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2503241
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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