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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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Issue Published : 115
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| Paper Title: | Colon Specific Drug Delivery Systems |
| Authors Name: | Ms. Shruti Ippalwad , Mr. Jitendra Shinde , Dr .Ashok Bhosale |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_202420
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| Published Paper Id: | IJRTI2504126 |
| Published In: | Volume 10 Issue 4, April-2025 |
| DOI: | |
| Abstract: | Abstract: Colonic Disorders: The paper highlights serious colonic disorders, particularly inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis, which can lead to severe complications like colon cancer. In India, there are over 66,000 cases of colon cancer annually, contributing to about 15% of cancer-related deaths in the country .Treatment Challenges: It discusses the limitations of traditional medication administration methods for treating IBD and other colon-related diseases. These methods often fail to deliver the drugs effectively to the affected areas, resulting in inadequate treatment .Need for Site-Specific Drug Delivery: The abstract emphasizes the importance of developing site-specific drug delivery systems that can effectively target the colon. Such systems can provide several therapeutic benefits, including:Delivering medication in its intact form as close to the target site as possible , Reducing the standard dosage required for treatment, Minimizing the risk of adverse side effects , Administration Methods: It mentions two primary methods for achieving colonic drug delivery: oral and rectal administration. However, rectal forms like enemas and suppositories are often ineffective due to their limited distribution capabilities. Therefore, oral administration is preferred, although it presents significant physiological challenges that must be overcome to ensure effective drug delivery .Overcoming Barriers: The abstract concludes by stating that effective colonic drug administration requires overcoming the main barrier of drug absorption or breakdown in the upper gastrointestinal tract. This is crucial for the successful treatment of serious colonic disorders, including colorectal cancer. |
| Keywords: | Colon targeting , pH dependent, Osmotic controlled system, Pulsincap system . |
| Cite Article: | "Colon Specific Drug Delivery Systems", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.b206-b213, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504126.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2504126
Registration ID:202420
Published In: Volume 10 Issue 4, April-2025
DOI (Digital Object Identifier):
Page No: b206-b213 Country: pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2504126 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2504126 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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