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Topical drug delivery is primarily used for localized treatment in dermatology, but modern techniques are now being explored to enhance its systemic effects as well. Traditionally, topical preparations serve roles such as antiseptics, antifungal agents, skin emollients, and protective agents. The effectiveness of these formulations depends on several factors, including the solubility of the drug, the duration of contact with the skin, its lipophilicity, and skin permeability. Gels represent a relatively new dosage form, created by trapping large volumes of aqueous or hydro-alcoholic fluids within a network of colloidal particles. These gel-based formulations typically offer quicker drug release than traditional topical products. However, a key drawback of gels is their limited ability to deliver hydrophobic drugs effectively. To address this, a combination of gels and emulsions, known as emulgels, has been developed. Emulgels merge the beneficial properties of both emulsions and gels. Emulsions themselves are aesthetically pleasing and can be easily rinsed off. Emulgels offer several advantages in dermatological applications, including being thixotropic, non-greasy, easy to spread and remove, emollient, non-staining, stable, biocompatible, transparent, and visually appealing. They are currently used for the topical delivery of drugs such as analgesics, anti-inflammatories, antifungals, and anti-acne agents, as well as in cosmetic products, with further potential still to be explored.
"Role of emulgel in topical drug delivery system", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.b656-b664, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504181.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator