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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
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| Paper Title: | STUDY OF ANTIOBESITY POTENTIAL OF "Aeginetia Indica" IN HFD-INDUCED OBESE RATS: A Review |
| Authors Name: | GARIMA , ARIJIT CHAUDHURI |
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| Author Reg. ID: |
IJRTI_202982
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| Published Paper Id: | IJRTI2504244 |
| Published In: | Volume 10 Issue 4, April-2025 |
| DOI: | |
| Abstract: | Aeginetia Indica is an underutilized bioactive compound containing flavonoids, phenolic acids and alkaloids which are popular for their anti-inflammatory properties. The plant is rich in antioxidants which can help in counteracting oxidative stress caused by high-fat diet (HFD), reducing risk of obesity-related complications. This study explores the antiobesity potential of Aeginetia Indica in a high-fat diet (HFD) induced obesity model using Sprague Dawley rats. Total 30 Rats were weighed first and then randomly allocated in to 5 groups having 6 rats in each group. Group 1 (Negative Control) Rats which are provided with oral normal diet and 0.9% normal saline throughout the study. Group 2 High fat rich diet control includes animals which were given high fat diet for 8 weeks. Group 3 (High fat diet + Test Drug in low dose) is treatment group which is given with low dose of out plant extract which we have obtained from plant Aeginetia Indica once a day for 42 days. Group 4 (High fat diet + Test Drug high dose) is treatment group which is given with high dose of out plant extract which we have obtained from plant Aeginetia Indica once a day for 42 days. Group 5 (High fat diet + Standard Orlistat 30 mg/kg) it include the standard group which is given the standard drug Orlistat 30mg per kg body weight once a day. All groups are fed with the high fat rich diet except normal control and their weight is measured weekly. Treatment impact of AI on body weight, liver function parameters and histopathological evaluations of liver and adipose tissue were investigated. The study on the Antiobesity potential of “Aeginetia Indica” in HFD-induced obese rats is expected to conclude that this novel formulation is a safe, effective and patient-friendly alternative to control the obesity. |
| Keywords: | Bioactive, Anti-Inflammatory, Histopathological, Formulation |
| Cite Article: | "STUDY OF ANTIOBESITY POTENTIAL OF "Aeginetia Indica" IN HFD-INDUCED OBESE RATS: A Review", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.c169-c174, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504244.pdf |
| Downloads: | 000359 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2504244
Registration ID:202982
Published In: Volume 10 Issue 4, April-2025
DOI (Digital Object Identifier):
Page No: c169-c174 Country: BILASPUR, HIMACHAL PRADESH, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2504244 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2504244 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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