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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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| Paper Title: | Recent advances in prevention and treatment of sickle cell anaemia -literature review |
| Authors Name: | Sivesh Sangar |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_170151
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| Published Paper Id: | IJRTI1704033 |
| Published In: | Volume 2 Issue 4, April-2017 |
| DOI: | |
| Abstract: | Sickle cell anaemia is a haemoglobinopathy which is inherited in the autosomal recessive manner. It causes haemolytic anaemia and reoccurring instances of vascular occlusion that gives rise to pain, this condition is common among people with African background. Previously, blood transfusion was carried out for patients having sickle cell anaemia. Recent advances include, hydroxyurea which is considered in patients having recurring episodes of acute chest syndrome with three or more crisis that requires hospitalisation. Another recent advance is by having the patient to undergo a bone marrow transplant but in order for the success of this treatment, an identical match is needed with at least 8 out of 10 human leukocyte antigen. Recent studies have demonstrated by carrying out aggressive transfusion therapies are not the best conservative and conventional approach towards a cure as it requires a long postoperative procedures by ingesting non-steroidal anti-inflammatory drugs. Conservative transfusion treatment is seen to be as effective as an aggressive regimen in preventing perioperative complications in patients with sickle cell anaemia, and the conservative approach resulted in only half as many transfusion-associated complications. Research is currently being carried out into hydroxyurea, gene therapy and bone marrow transplants as well a huge range of new drugs are being tested clinically for the treatment of sickle cell anaemia. With these new therapies and treatment procedures, it may be possible to help improve the anaesthetic course of the patients with sickle cell disease as well as reduces postoperative complications and allow the patient to be discharged out of the hospitals in a faster time. |
| Keywords: | Sickle cell anaemia, therapies, treatment |
| Cite Article: | "Recent advances in prevention and treatment of sickle cell anaemia -literature review", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.2, Issue 4, page no.128 - 130, April-2017, Available :http://www.ijrti.org/papers/IJRTI1704033.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI1704033
Registration ID:170151
Published In: Volume 2 Issue 4, April-2017
DOI (Digital Object Identifier):
Page No: 128 - 130 Country: Chennai, Tamil Nadu , India Research Area: Biological Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI1704033 Published Paper PDF: https://www.ijrti.org/papers/IJRTI1704033 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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