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ABSTRACT: AIM: To assess the prevalence of lipid abnormalities in patients with diabetes mellitus. OBJECTIVE: To asses the lipid abnormalities such as VLDL,LDL,HDL in diabetic patients. MATERIALS AND METHODS: This was a cross-sectional study of 50 Diabetic patients in Saveetha Medical College and hospitals. Patients' VLDL, LDL, HDL and total cholesterol were recorded. BACKGROUND: Hyperlipidemia is common in diabetic patients. The roles of insulin deficiency, insulin resistance, obesity, and genetic factors are discussed in relation to their effects on lipoprotein production and catabolism. The most important defect in insulin-deficient subjects appears to be a deficiency of lipoprotein lipase, which is responsible for the removal of the triglyceride-rich lipoproteins. In non-insulin-dependent subjects there is evidence for a removal defect as well as, in some patients, for overproduction of VLDL-triglyceride. Cholesterol levels may be elevated and it is important to distinguish between VLDL, LDL, and HDL as the causes for these increases. HDL-cholesterol levels may be increased in insulin-dependent subjects, whereas they may be decreased in obese non-insulin-dependent patients. Mild elevations of LDL-cholesterol may occur in inadequately controlled type I and II diabetic patients, while elevated VLDL may raise the serum cholesterol in addition to the triglyceride levels. REASON FOR RESEARCH : With increased levels of Diabetic patients, the need to understand various aspects of the disorder is important. Diabetic hyperlipidemia should be viewed as resulting from an interaction between the diabetic syndrome, the genetic background of the patient, and the environment.
Keywords:
diabetes mellitus, lipid profile, abnormalities
Cite Article:
" TO ASSESS THE PREVALENCE OF LIPID ABNORALITIES IN PATIENTS WITH DIABETIC MELLITUS ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.2, Issue 10, page no.32 - 34, October-2017, Available :http://www.ijrti.org/papers/IJRTI1710005.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator