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ABSTRACT: Worldwide essential hypertension has been responsible for 9.4 million deaths. Hypertension is major risk factor for cardiovascular complications like myocardial infarction, retinopathy, arrhythmias and sudden death. Our knowledge is still limited about the cause of increased cardiovascular risk in essential hypertension. Despite decades of research, the mechanism involved in the development of essential hypertension is still poorly understood. Autonomic nerves supplying the heart may also be involved in hypertension causing cardiac autonomic neuropathy (CAN). So the present study was undertaken to assess the cardiac autonomic functions in essential hypertensive patients as compared to normotensive subjects. We studied E: I ratio, 30:15 ratio tests for parasympathetic functions and sustained hand grip test, cold pressor test for sympathetic functions. It was found that statistically significant rise in diastolic blood pressure in hypertensive group (p<0.05) over normotensive group in both CPT and SHG. There was statistically significant rise in heart rate in hypertensive group (p<0.05) over normotensive group in E: I ratio, 30:15 ratio tests. So it can be concluded that there is definite cardiovascular autonomic dysfunction in stage 1 essential hypertensive patients as compared to normotensive subjects. There is increased sympathetic and decreased parasympathetic activity in stage 1 essential hypertension. Key words: Hypertension, Autonomic functions, Baroreceptor reflex function, cardiac autonomic neuropathy.
"A Comparative Study Of Cardiovascular Autonomic Functions In Stage 1 Hypertensive Subjects And Normotensive Subjects.", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.2, Issue 12, page no.8 - 13, December-2017, Available :http://www.ijrti.org/papers/IJRTI1712002.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator