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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
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| Paper Title: | Formulation and in Vitro evaluation of Nifidepine immediate and sustained release encapsulated mini tablets |
| Authors Name: | Heena Tasneef , Dr.Abdul Azeez Basha |
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| Author Reg. ID: |
IJRTI_181311
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| Published Paper Id: | IJRTI2008005 |
| Published In: | Volume 5 Issue 8, August-2020 |
| DOI: | |
| Abstract: | Solid oral dosage forms are most acceptable dosage forms especially tablets are most generally accepted by people of various age groups. Mini tablets are tablets with a diameter adequate to or smaller than 2–3 mm. Mini tablets are multiple unit dosage forms and are advantageous than pellets or the other oral dosage forms as they're easy to manufacture and stability problems are less(1). Many types of mini tablets are there like bio adhesive mini tablets, pH responsive mini tablets, gastro retentive mini tablets, paediatric mini tablets, oral disintegrating mini tablets. These mainly reduce the variation among subjects. The review emphasises on advantages of mini tablets, types, methods of manufacturing and modes of administration and evaluation of mini tablets.of the present study was to develop Bilayered tablets of Nifedipine which is used for treatment of Angina pectori.Bilayered tablet contains two layers. We can formulate first layer into immediate release and second layer into sustained release for desired action.Nifedipine have half-life 2hrs make the drug suitable for immediate release.In this formulation using material Nifedipine,Sodium starch glycolate,Lycoat,Crosspovidone,Carbopol,Guar gum,HPMC K4M ,Microcystalline cellulose,Magnesium stearate Talc.and method of prepartion are used as dircet compression method for both immediate and sustain release.(2).The post and pre ompression evaluation as been done and then compared with marketed formulation. |
| Keywords: | Mini tablet,Angina pectori,Direct compression. |
| Cite Article: | "Formulation and in Vitro evaluation of Nifidepine immediate and sustained release encapsulated mini tablets", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 8, page no.22 - 27, August-2020, Available :http://www.ijrti.org/papers/IJRTI2008005.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2008005
Registration ID:181311
Published In: Volume 5 Issue 8, August-2020
DOI (Digital Object Identifier):
Page No: 22 - 27 Country: Hyderabad, Telangana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2008005 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2008005 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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