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Paper Title:
A STUDY ON PREVALENCE OF CANDIDA ALBICANS IN VULVOVAGINAL CANDIDIASIS AND THEIR PHENOTYPIC CHARACTERIZATION WITH ANTIFUNGAL SUSCEPTABILITY PATTERN IN A TERTIARY CARE HOSPITAL, LUCKNOW, INDIA
Background: Vaginal candidiasis is a common gynaecological finding among women worldwide. This study was carried out to determine the prevalence of vulvovaginal candidiasis (VVC) along with speciation of Candida with special reference to its antifungal susceptibility pattern to fluconazole and also to evaluate the risk factors responsible for VVC in patients attending our tertiary care hospital in Lucknow, India.
Materials and Methods: This study was conducted in the Department of Microbiology, Prasad Medical College and Hospital, Lucknow, India during the period of 2018 to 2020. The study group consisted of clinically suspected 180 cases of vulvovaginitis candidiasis the age group of between 15 to 56 years. The collection of data include name, age, complaints like vaginal discharge, pain and itching, duration of illness whether acute or chronic, any past history of presenting episode, any systemic diseases such as diabetes/hypertension/tuberculosis. An informed written consent was obtained from all patients, attending Obstetrics & Gynecology out patients Department. Samples were collected upon inserting a sterile vaginal speculum into vagina; two high vaginal swabs, one after the other, were taken by a sterile cotton wool swab into the posterior vaginal fornix and rotated gently and High vaginal swabs were subjected to direct 10% KOH wet mount microscopy, Gram stain, culture onto Sabouraud’s dextrose agar (SDA) & 5% sheep blood agar and susceptibility testing to fluconazole was performed
Results: Candida albicans were isolated in 83(46%) of total clinically suspected case and 97(54%) were non candida albicans and antifungal susceptibility test carried out on the 83 isolates as recommended by Clinical and Laboratory Standards Institute (CLSI)
Conclusion: Candida albicans was the predominant species responsible for VVC infection and commonly used antifungal drugs clotrimazole, voriconazole and fluconazole were most effective.
"A STUDY ON PREVALENCE OF CANDIDA ALBICANS IN VULVOVAGINAL CANDIDIASIS AND THEIR PHENOTYPIC CHARACTERIZATION WITH ANTIFUNGAL SUSCEPTABILITY PATTERN IN A TERTIARY CARE HOSPITAL, LUCKNOW, INDIA", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 7, page no.464 - 467, July-2022, Available :http://www.ijrti.org/papers/IJRTI2207069.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator