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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21604
Article Published : 8531
Total Authors : 22438
Total Reviewer : 805
Total Countries : 159
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| Paper Title: | TO STUDY THE RECEPTOR STATUS BEFORE AND AFTER NEOADJUVANT CHEMOTHERAPY IN BREAST CARCINOMA |
| Authors Name: | Dr. Nityasha Dalal , Dr. Ipsita Aggarwal , Dr. S. Dalal , Dr Shiva Asati , Dr. Harsha Kamalhans, Dr. Sachin Bharadwaj |
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IJRTI_183999
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| Published Paper Id: | IJRTI2209016 |
| Published In: | Volume 7 Issue 9, September-2022 |
| DOI: | |
| Abstract: | Breast cancer is a major public health problem for women throughout the world, being the leading cause of cancer death amongst females after carcinoma lung. Treatment of carcinoma breast is multimodal including surgery, radiotherapy, chemotherapy, and the hormonal therapy depending upon the HPE and IHC reports((ER, PR, HER-2-NEU and Ki 67). We conducted an observational study in which the HPE and IHC reports before and after the administration of systemic therapy in the patients with locally advanced breast cancer (LABC) was compared. The preoperative HPE and IHC reports were obtained by the core needle biopsy. Response of the disease so obtained after the NACT was evaluated with RECIST criteria and depending on the type of response (complete and partial) , patients were subjected to surgical treatment (Modified radical mastectomy ) The final reports of HPE and IHC of MRM specimen thus obtained was compared with preNACT HPE and IHC eeport.. From our study we concluded that NACT brings about a change in the ER, PR, HER-2-NEU and Ki-67 receptor status in carcinoma breast which can change the management of the patient in view of target based therapy and hormonal therapy in the post operative period. |
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| Cite Article: | "TO STUDY THE RECEPTOR STATUS BEFORE AND AFTER NEOADJUVANT CHEMOTHERAPY IN BREAST CARCINOMA", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.132 - 134, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209016.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2209016
Registration ID:183999
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 132 - 134 Country: -, -, - Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2209016 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2209016 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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