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Tretinoin is a naturally occurring acid of retinol. Tretinoin binds to and activates
retinoic acid receptors (RARs), thereby including changes in gene expression that lead
to cell differentiation, decreased cell proliferation, and inhibition of tumorigenesis.
Retinoids such as tretinoin are an important regulator of cell reproduction,
proliferation, and differentiation, and are used in the treatment of acne and
photodamaged skin and to manage keratinization disorders such as ichthyosis,
keratosis follicularis.
Topical tretinoin modifies fine wrinkles and certain other features of human skin
damaged by exposure to the sun, but histologic changes do not account for this
improvement. In mice photodamage induced by ultraviolet light, effacement of
wrinkles by tretinoin is correlated with dermal collagen synthesis but not with
histologic changes. Tretinoin minimizes the appearance of wrinkles, bolsters skin’s
thickness and elasticity, slows down the breakdown of collagen which helps keep skin
firm, and lightens brown spots by sun exposure. Retinoids were first introduced to the
market in the early 1970s as an aid in acne-fighting drugs. Since then they have been
used to treat psoriasis, warts, wrinkles, and blotchiness caused by sun exposure and
aged skin.
This study provides an overview of the market trends regarding the use of peptides in
anti-aging products, providing meaningful data for scientists involved in the
development of new peptides to identify opportunities for innovation in this area to
achieve desired results in making skin healthy
Keywords:
Cite Article:
"Tretinoin a peptide in anti-aging therapy an overview", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.191 - 200, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209025.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator