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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

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Paper Title: Tretinoin a peptide in anti-aging therapy an overview
Authors Name: Aditi Lakade , Rutuja Aher
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IJRTI_183570
Published Paper Id: IJRTI2209025
Published In: Volume 7 Issue 9, September-2022
DOI:
Abstract: Tretinoin is a naturally occurring acid of retinol. Tretinoin binds to and activates retinoic acid receptors (RARs), thereby including changes in gene expression that lead to cell differentiation, decreased cell proliferation, and inhibition of tumorigenesis. Retinoids such as tretinoin are an important regulator of cell reproduction, proliferation, and differentiation, and are used in the treatment of acne and photodamaged skin and to manage keratinization disorders such as ichthyosis, keratosis follicularis. Topical tretinoin modifies fine wrinkles and certain other features of human skin damaged by exposure to the sun, but histologic changes do not account for this improvement. In mice photodamage induced by ultraviolet light, effacement of wrinkles by tretinoin is correlated with dermal collagen synthesis but not with histologic changes. Tretinoin minimizes the appearance of wrinkles, bolsters skin’s thickness and elasticity, slows down the breakdown of collagen which helps keep skin firm, and lightens brown spots by sun exposure. Retinoids were first introduced to the market in the early 1970s as an aid in acne-fighting drugs. Since then they have been used to treat psoriasis, warts, wrinkles, and blotchiness caused by sun exposure and aged skin. This study provides an overview of the market trends regarding the use of peptides in anti-aging products, providing meaningful data for scientists involved in the development of new peptides to identify opportunities for innovation in this area to achieve desired results in making skin healthy
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Cite Article: "Tretinoin a peptide in anti-aging therapy an overview", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.191 - 200, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209025.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2209025
Registration ID:183570
Published In: Volume 7 Issue 9, September-2022
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Page No: 191 - 200
Country: Nira shivtakrar, MAHARASHTRA, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2209025
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2209025
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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