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Now- a- days, green synthesis of metallic nanoparticles is a growing area of research because of their potential therapeutic applications for various diseases. In the present work, bimetallic silver nickel nanoparticles (BMNPs) are synthesized from silver nitrate (AgNO3) and cobalt nitrate (Ni (NO3)2) precursor solutions using aqueous leaf extract of Aerva lanata as bioreducing, stabilizing and capping agent. The synthesized BMNPs were characterized using UV–Vis spectroscopy, FTIR, SEM, EDX, XRD and TEM analyses. The cytotoxic response was assessed by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. These biogenic Silver nickel BMNPs were found to be significantly toxic to MCF-7 cells (human breast cancer cells) via induction of apoptosis.
Keywords:
Bimetallic nanoparticles (BMNPs), Aerva lanata(AL), Phytomolecules and invitro cytotoxicity
Cite Article:
"Anticancer Activity of Phytogenic Bimetallic Nanoparticles against MCF-7 Cells", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.796 - 800, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209105.pdf
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000205212
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator