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Myocarditis is an inflammation of the myocardium, with on histological examination an infiltrate of inflammatory cells and signs of myocyte necrosis, the diagnosis of acute myocarditis must be considered in the presence of signs of heart failure in the absence of coronary or valvular disease.
Acute and subacute myocarditis are most often of infectious origin, viral, they can also be linked to parasitosis, to the intake of toxic substances, in particular the case of immunosuppressive treatments and during autoimmune pathologies.
Their clinical expression and prognosis are highly variable, making their diagnosis and treatment difficult.
The current incidence of the disease is, moreover, also difficult to establish because the diagnosis of certainty depends, in the state, on the realization of myocardial biopsies and these are not systematically carried out, nor even justified. When the clinical presentation does not include any signs of severity, the disease is generally self-limiting without specific treatment.
However, the condition can also present as cardiogenic shock or sudden death. The etiology of myocarditis has a predictive prognostic value and directs, in certain cases, towards a specific treatment.
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Cite Article:
"Methotrexate a cause of myocarditis, Myth or reality?", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.832 - 834, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209110.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator