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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21604
Article Published : 8531
Total Authors : 22438
Total Reviewer : 805
Total Countries : 159
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| Paper Title: | ANALYTICAL METHOD DEVELOPMENT FOR THE DETERMINATION AND QUANTIFICATION OF RAMIPRIL IN PHARMACEUTICAL FORMULATION BY HPLC |
| Authors Name: | Dipak Patil , Shyam W. Rangari , Prashant P. Nikumbh , Sandip S. Chaudhari , Mayur R. Bhurat |
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IJRTI_184066
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| Published Paper Id: | IJRTI2209124 |
| Published In: | Volume 7 Issue 9, September-2022 |
| DOI: | |
| Abstract: | The present work explains the development and validation of a simple and reliable RP-HPLC method for the quantitative determination of ramipril (RMP). Chromatography was carried out by reversed-phase technique on a Fortis C18 (100 mm × 4.6 mm; 2.5 μm particle size). The optimized mobile phase was consisted of Methanol and citric acid sodium citrate buffer solution (50:50 v/v) having pH 3.0. The retention times were 3.645 min for RMP. The detection was carried out at 270 nm and a column temperature of 25 °C. The method was evaluated for the various validation parameters, such as linearity, accuracy, precision, LOD, LOQ, specificity, selectivity, and sample stability. The proposed method was validated and successfully applied for the analysis of pharmaceutical formulations and laboratory-prepared mixture containing Ramipril respectively. |
| Keywords: | Ramapril, LOD, LOQ, PR-HPLC |
| Cite Article: | "ANALYTICAL METHOD DEVELOPMENT FOR THE DETERMINATION AND QUANTIFICATION OF RAMIPRIL IN PHARMACEUTICAL FORMULATION BY HPLC", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.910 - 915, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209124.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2209124
Registration ID:184066
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 910 - 915 Country: Aurangabad, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2209124 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2209124 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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