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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 113
Article Submitted : 18006
Article Published : 7746
Total Authors : 20484
Total Reviewer : 747
Total Countries : 140
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| Paper Title: | Analytical Method Development and Validation for Simultaneous Estimation of Olanzapine and Escitalopram Oxalate in bulk pharmaceutical dosage form by RP-HPLC Method. |
| Authors Name: | Rupali Kobarne , Manish Raskar , Pallavi Jadhav |
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IJRTI_184588
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| Published Paper Id: | IJRTI2211045 |
| Published In: | Volume 7 Issue 11, November-2022 |
| DOI: | |
| Abstract: | A simple, sensitive, accurate, precise, linear, reproducible, ecofriendly, economic and fast HPLC method has been developed. The proposed method was validated for according to ICH guidelines. Reverse phase HPLC method has been developed for simultaneous estimation of anti-psychotic drug Olanzapine and antidepressant drug Escitalopram Oxalate in bulk drug and dosage forms. The mobile phase used for to developed the method was Methanol: Water (80:20 v/v). The flow rate of mobile phase delivery is 1.0 ml/min. at a wavelength detection at 217nm. The retention time of Olanzapine and Escitalopram Oxalate were 2.21 min 3.09 min. respectively. The developed method was accurately validated follows all the guidelines prescribed by the ICH. The proposed method used for determination of concentration of these drugs in bulk and combined dosage forms. |
| Keywords: | RP-HPLC, Olanzapine, Escitalopram oxalate, Validation and Pharmaceuticals. |
| Cite Article: | "Analytical Method Development and Validation for Simultaneous Estimation of Olanzapine and Escitalopram Oxalate in bulk pharmaceutical dosage form by RP-HPLC Method.", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 11, page no.306 - 311, November-2022, Available :http://www.ijrti.org/papers/IJRTI2211045.pdf |
| Downloads: | 000205277 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2211045
Registration ID:184588
Published In: Volume 7 Issue 11, November-2022
DOI (Digital Object Identifier):
Page No: 306 - 311 Country: Ahmednagar, Maharastra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2211045 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2211045 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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