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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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| Paper Title: | ZOLLINGER-ELLISON SYNDROME AN OVERVIEW |
| Authors Name: | Arati Machale , Ajay sable , Ashwini Andhale , Santosh Waghmare , Hemant Kamble |
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IJRTI_184606
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| Published Paper Id: | IJRTI2211046 |
| Published In: | Volume 7 Issue 11, November-2022 |
| DOI: | |
| Abstract: | Zollinger and Ellison (1955) described a syndrome of recurrent gastric ulceration and gastric hypersecretion associated with pancreatic islet cell tumors. For many years, doctors and surgeons have agreed that a total gastrectomy is the best treatment. Cimetidine, a histamine H2 receptor antagonist, inhibits the basal stimulation of gastric acid secretion and promotes the healing of gastric and duodenal ulcers. ZES is a rare cause of gastric ulcers, accounting for only 0.1-1% of ulcers. . A perforated gastric ulcer was suspected and urgent surgical intervention was required. A tumor lesion in the head of the pancreas was then identified and repaired using the Whipple technique. Pathological results showed tumors indicative of neuroendocrine tumors. The incidence of ZES in the United States is 1-3 new cases per million people per year, making it a rare condition. The most common symptom of ZES is pelvic pain associated with peptic ulcer disease. More than 90% of gastrinoma patients develop upper gastrointestinal ulcers during the course of the disease. Similar to typical idiopathic ulcer disease, ZES is usually characterized by discrete ulcers, 75% of which occur in the first segment of the duodenum. Patients with ZES may also have recurrent, multiple, and atypical focal ulcers. In this surgery, a special endoscope called an endoscope uses ultrasound to treat the pancreas. The secretin stimulation test is the provocative test of choice, can diagnose ZES because it is sensitive, easy to use, and has no negative side effects. |
| Keywords: | Zollinger-Ellison syndrome (ZES), peptic ulcer disease, gastrectomy, gastrinoma. |
| Cite Article: | "ZOLLINGER-ELLISON SYNDROME AN OVERVIEW", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 11, page no.312 - 319, November-2022, Available :http://www.ijrti.org/papers/IJRTI2211046.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2211046
Registration ID:184606
Published In: Volume 7 Issue 11, November-2022
DOI (Digital Object Identifier):
Page No: 312 - 319 Country: Pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2211046 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2211046 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
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