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Background: Hypertension is a very common medical problem worldwide. It is under-recognized and poorly treated. There is scope for significant improvement in hypertension therapy since only one-third of hypertension in India is diagnosed, of which only one-third is well treated and well controlled. Objective: The main objective of this study is to evaluate the current prescription practice of antihypertensive drugs in newly diagnosed hypertensive patients and to determine whether the prescription pattern is in adherence with ISH 2020 guidelines for the management of hypertension. Method: A prospective observational study was carried out for six months in a tertiary care hospital across the medical and cardiology services. Result: A total of 73 prescriptions were analyzed. Our results revealed that 54.80% were male while 45.20% were female, of which 49 (67.1%), 10 (13.7%), 6 (8.2%), 5 (6.8%) patients were receiving one, two, three and four anti-hypertensive drugs, respectively. Only 3 patients were on non-pharmacological treatment. In our study out of a total of 61 (83.56%), patients received essential standard care and 12 (16.43%) patients received optimal standard care, among which the majority, 64 (87.67%) patients achieved the targeted BP control and 9 (12.32%) didn't achieve the target BP. The most commonly prescribed anti-hypertensive drugs, whether in mono or combination regimens, were CCBs (amlodipine, cilnidipine), followed by ARBs (telmisartan, valsartan), diuretics (hydrochlorothiazide, torasemide, furosemide, mannitol), β-blockers (atenolol, bisoprolol, metoprolol), and ACE inhibitors (ramipril, enalapril). The mean systolic blood pressure Mean±SD of SBP/DBP in the final and first visit was 129.98±13.13/84.30±9.45 mmHg and 154.12±13.21/92.72±14.08 mmHg, respectively. A significant reduction (p<0.0001) in systolic and diastolic blood pressure was observed. Conclusion: The CCBs (Cilnidipine) and ARBs (Telmisartan) were the drugs of choice for hypertensive patients as a single drug and combination drug therapy. As per the International Society of Hypertension (ISH), 2020 guidelines, the majority of the subjects have achieved targeted BP goals. Our results reveal that the prescription practice of anti-hypertensive medication and adherence to guidelines is optimal at the study site.
Keywords:
Newly diagnosed hypertension, prescription practice, antihypertensive, ISH
Cite Article:
"Evaluate the current prescription practice in newly diagnosed hypertensive patients; Treatment comparison with ISH 2020 Guidelines", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 1, page no.95 - 108, January-2023, Available :http://www.ijrti.org/papers/IJRTI2301017.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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