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“An adverse drug reaction may be defined as an untoward clinical manifestation resulting from administration of a particular drug”. The most common target organ for adverse drug reaction is the skin. Monitoring the CADR will help the health care professionals in better patient care and better use of drugs. The aim of this study was to assess the type of cutaneous adverse drug reaction. It is a prospective observational study carried out in a tertiary care hospital and data on CADR was collected from the day-to-day ward rounds. Primary ends points of this study included the type of reaction, the time of onset, drugs causing the CADRs and treatment was studied. The study included 60 cases ,most of the reaction took one day for onset and the commonest cutaneous reaction was EME(43.3%) treatment given was Inj.Chlorpheniramine(40%) and Urticaria (13.3%) treatment given was Inj.Chlorpheniramine(50%) , the common causative drug class were antibiotics(43.3%), corticosteroids (8.3%) and NSAIDs (8.3%). Common route of administration was oral (50%) and IV (45%). The most common risk factor was age (38.3%) and intercurrent disease (33.3%). CADR which required intervention to prevent permanent impairment/damage 53 (83.3%) cases, life threatening 5 (3.3%) cases, and caused disability was seen in 2 (3.3%) cases.
Monitoring of drug reactions should be prioritized in every health care institution to improve the quality of life of patient.
Keywords:
Cutaneous Adverse Drug Reaction (CADR), Adverse Drug Reaction, Stevens Johnson Syndrome (SJS), Exantamateous Maculopapular Eruption (EME), Assessment, Treatment
Cite Article:
"CUTANEOUS ADVERSE DRUG REACTION IN A TERTIARY CARE HOSPITAL-A PROSPECTIVE OBSERVATIONAL STUDY", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 1, page no.244 - 251, January-2023, Available :http://www.ijrti.org/papers/IJRTI2301038.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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