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Background: The kidney is the structural and functional unit responsible for regulating homeostasis, equilibrium(acid-base) and electrolytes, also kidney plays a major role in the disposition of many drugs. CKD patients were commonly present with several other comorbidities of which HTN and DM are the most common. a large number of medications usually prescribed to CKD patients that are complicated and require dosing and frequent monitoring. The objective of the study is to analyze the prescription pattern of medications in CKD patients Method: a prospective observational study on the prescription pattern of medications in chronic kidney disease patients which is based on the collection of data on a daily visit to the department of nephrology, medicines and HICU in tertiary care hospital. The patient who met the criteria were involved in the study. WHO Prescribing Indicator, ATC classification of drugs and therapeutic class drug distribution were used for the analysis of drugs. Result: Out of 60 collected cases, 70% were male and 30% were female. The study population were also having comorbidities along with CKD in which HTN was the highest among CKD patients with 75% followed by DM (68%), Anemia (30%), Respiratory Disorder (27%), CVD (18%), Thyroid Disorder (15%) and UTI (13%). WHO drug prescribing indicator showed that the average number of drugs prescribed per patient was 12, the percentage of drugs prescribed by generic name was (390) 54%, the percentage of a patient with an injection prescribed was (246) 34%, the percentage of drugs prescribed from essential medicine list was (580) 80%. Antihypertensive drugs (163) 22.5% were commonly used drugs followed by vitamins (141)19.44%, minerals (99) 13.65%, antimicrobial (93) 13.2%, hemopoietic agents (53) 7.3%, anti-diabetic agent (52) 7.2% and hypolipidemic agent (39) 5.4%. Conclusion: An overall understanding of medications used in CKD management, their complications and comorbidities associated with it, helps physicians and prescriber in better control and management of CKD patients, adverse effects and toxicities of the drugs, which in turn leads to improving patient compliance to treatment therapy. After the analysis of all the CKD cases, it was found that symptoms along with the comorbidities were managed accordingly. Meanwhile, the rationality of prescribing was followed.
"Prospective observational study on the prescription pattern of medications in chronic kidney disease patients at tertiary care hospital", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 2, page no.429 - 438, February-2023, Available :http://www.ijrti.org/papers/IJRTI2302071.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator